Development and Evaluation of Novel Small Molecules Targeting Lysophosphatidic Acid Receptor 1 for the Treatment of Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC), characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (HER2) expression, exhibits high invasiveness, metastatic potential, and poor prognosis. Current chemotherapy for metastatic TNBC is associated with low response rates and short progression-free survival. It is imperative to find new therapies for this […]

Read More
Veterinary Disease Detection Using Machine Learning and Deep Learning Architectures

In recent advancements, researchers are leveraging deep learning and machine learning for improving medical care, particularly within the veterinary field. The development of smart, wearable biosensing devices, equipped with non-invasive sensors and integrated with machine learning algorithms, facilitates real-time health monitoring. Continuous monitoring of health data through these devices offers valuable insights into adverse health […]

Read More
Health monitoring and control of masonry structures

The development of international standards and codes led to the creation of safe and properly designed fully cured masonry structures capable of withstanding lateral loads induced by wind or earthquakes. However, as the age of masonry plays an important role on its strength, it was reported that before it is fully-cured, masonry is vulnerable to […]

Read More
Assessment the rheological behavior of polybutene polymers as viscosity modifiers in lubricating oils

Lubricants can lose viscosity when exposed to high temperatures, leading to engine damage. Viscosity modifiers can be added to address this issue. When applying these additives to lubricating oils, it becomes vital to assess the rheological behavior. As the microstructure of these additives play a golden role in their functionality in lubricating oils, it’s fruitful […]

Read More
Human connections to nature in Niagara Peninsula Watershed protected areas

This research aims to understand how visitors to Niagara Peninsula watershed (NPW) protected areas connect with nature, their intentions for pro-environmental behaviour, and the actions they take to care for nature, the environment, and natural resources. We also synthesize knowledge about interventions taken by park managers around to world to promote pro-environmental and stewardship behaviours […]

Read More
The Feasibility of Applying Pescatourism in Small-scale Fishery in Japan

Small-scale Fisheries (SSF) communities are vulnerable to several drivers and their viability remains a challenge. To innovatively alleviate the vulnerabilities and follow sustainable pathways towards viability of SSF, Pescatourism, which is a popular type of fishing tourism in Europe, has been proposed as an alternative. However, literature has shown that Pescatourism’s contributions to local economies […]

Read More
Nature-based solutions for health and economic-informed microclimate management

The research project promotes urban sustainability and the impact of preserving natural assets on health and the economy. It focuses on climate change adaptation and climate hazard mitigation, including, extreme heat, air quality, flooding, and high wind events. The research proposes a framework to predict and mitigate the impact of climate hazards on public health […]

Read More
Machine learning approach to monitoring and decarbonizing mineral processes

Within Canada’s commitment to the 2030 Agenda for Sustainable Development, a pivotal goal involves taking immediate action to combat climate change and its far-reaching effects. The specified target is a 40% to 45% reduction in the country’s total greenhouse gas (GHG) emissions below 2005 levels by 2030. To transition away from fossil fuels and embrace […]

Read More