Quantum Deep Neural Nets for Spatial-Temporal Problems

Atmospheric behaviour will change substantially with Climate Change and is one of our generation’s most pressing challenges. The world requires accurate estimates of future the impacts from droughts, floods, heat waves, increase hazards, from freezing rain to hurricane to plan, prepare and mitigate. Combatting climate change requires reducing our emissions in a strategic way. Current […]

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Optimizing the delivery of ministring DNA (msDNA) to the central nervous system for use in gene therapy applications

Gene therapy has risen as one of the more promising treatment options for disorders of the central nervous system (CNS). Using modified viruses to deliver genetic material has shown success however has several disadvantages including increased safety risks. Using a non-viral vector system has the potential to overcome many of the challenges that arise with […]

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Reusable carboxylic acid solvents

The proposal focuses on using safe, non-toxic fatty acids as bio-derived and recyclable solvents for extraction of biomass polymers/waste plastics (e.g. wood chips, woody or agricultural biomass, algae, oil bottles). We will employ a new approach using fatty acids that are responsive to pH changes such that their properties can be switched from hydrophobic to […]

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Investigating Cannflavins A and B as Inhibitors of TrkB Signaling for Treatment of Glioblastoma Multiforme

Glioblastoma is the most common type of adult brain cancer. Glioblastoma tumors are very aggressive because these cells can rapidly invade deep into healthy tissue, which makes them particularly difficult to attack with current treatment options including surgery, radiotherapy, and chemotherapy. Therefore, better pharmaceutical strategies to neutralize glioblastoma cells without damaging surrounding healthy cells is […]

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Establishing nutritional attributes for plant-based meats and alternatives: Development of literature review and validation plan

Plant-based meat alternatives are made using plant sources and which mimic meat in their appearance and texture. Vegan and vegetarian consumers prefer these products to meat, but many more Canadians stand to benefit from them as they transition towards diets relying more heavily on plant-based foods for ethical, environmentally sustainability, and health reasons. Consequently, the […]

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Studying the biodegradability of eco-friendly straws in prospective disposal environments

The existing use of plastics is overwhelming, but unfortunately, non-biodegradable plastic is majorly used, which results in waste accumulation and danger to marine life. Efforts are being made to produce biodegradable plastic products, such that it degrades substantially after disposal and does not hurt our environment. However, there are many biodegradable plastics, with variable biodegradation […]

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Advancing a novel therapeutic for the prevention of hypoglycemia in rodent models of type 2 diabetes (T2DM) and in phase 1 and 2 human clinical trials for type 1 diabetes

Hypoglycemia or low blood sugar is a phenomenon that results from excess insulin or strenuous exercise in diabetic patients. If untreated, this can quickly lead to dizziness, seizures and even death. In healthy individuals, the body is able to compensate for these fluctuations and restore blood sugars to normal levels by lowering insulin and raising […]

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