Application of Novel DNA vectors in CNS gene and cell therapy

This project will test how well different DNA-based therapies work in the brain and body using a mouse model. Mice will receive either a high or low dose of the therapy, and their response will be tracked through imaging, blood tests, and tissue analysis. The goal is to measure how much of the DNA reaches […]

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Advancing a Learning Health System for Mood Disorders

Many patients with mood disorders, which include major depression and bipolar disorder, continue to experience symptoms even after receiving treatment. Traditional research methods have helped improve care but often don’t reflect the realities of clinical practice, which slows progress in applying research to improve services. This project aims to support St. Joseph’s Healthcare Hamilton (SJHH) […]

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Juniper Genomics Social Media Monitoring and Strategy Development internship

Juniper Genomics is a forward-thinking company that uses advanced genetic technology to help people going through IVF (in vitro fertilization) make more informed decisions and improve their chances of having a successful pregnancy. While their science is cutting-edge, they currently lack a strong digital presence, especially on social media. This makes it hard for potential […]

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Patient to provider AI message drafting in hospital-based outpatient care, a mixed-methods study exploring integration in care and impact

Patients can use secure messages to communicate with their healthcare providers through patient-facing patient portals. While patients like the use of secured messaging, it also increases the workload burden for providers, and as such, providers often do not offer it to patients. With recent years of technological innovation, electronic hospital records software has developed AI-generated […]

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Working Together: Building Community, Access to Birth Certificates, and the Social Determinants of Health

Working Together (WT) is a multi-agency collaborative project supporting frontline organizations affiliated with the Thunder Bay ID Action Group to provide Personal Identification Services (PID) for people who are marginalized and low income. This project employs a community-based action-oriented research approach to better understand the role played by existing ID services in the region and […]

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Fraud-Centric Merchant Embeddings

Mastercard works with improving and securing payments of millions of cardholders and merchants. One of the primary objectives of Mastercard’s work is to detect and prevent fraudulent payments. There are several ways of committing such fraud, often such fraud can happen due to vulnerability of the merchant to such fraudulent threats and several other underlying […]

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Enhancing the Accuracy of Digital Twin Simulation with Machine Learning and Predictive Analytics

Manufacturing companies often face challenges like unexpected equipment breakdowns, shifting production needs, and resource shortages or surpluses, which can lead to delays in production schedules. Traditional systems struggle to manage these issues effectively. Our project introduces a better solution using Digital Twin (DT) technology, which creates a real-time digital replica of a factory’s operations. This […]

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Meta learning of hyperparameters for parallel and distributed Gradient Boosted Decision Trees on big data

When Kinaxis trains its machine learning models, it does so on two time scales. Every week or so, it looks at around 10 billion sales records and tries to learn the rapidly-changing “parameters” that best describe this data. Every 3-6 months, it updates 10 thousand collections of “hyperparameters” that govern the parameter-learning process. Kinaxis would […]

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Numerical modelling of enhanced superplastic forming of titanium alloy aerospace parts

Titanium alloys are used to manufacture aerospace components that require high strength at high operating temperatures such as fan blades, heat shields and jet engine exhaust cones. Parts that have complex geometries are commonly formed at high temperature (around 900°C) so as to achieve maximum ductility during the forming process. By applying a small oscillating […]

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Enhanced Wireless Power Transfer via Multisource Thermophotovoltaic Systems

The objective of this research project is to design, fabricate and test a prototype wireless power transmission system that uses a thermophotovoltaic (TPV) system to receive the power beam. By using a TPV system as the receiver (instead of a photovoltaic cell) the electromagnetic radiation can have almost any wavelength. This opens a broad range […]

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