Preclinical evaluation of novel meningococcal vaccines

Neisseria meningitidis (Nme) is a bacterial pathogen that often colonizes the upper respiratory tract of humans without symptoms, but which may also develop into rapidly-progressing sepsis and meningitis that can be fatal. Nme has evolved elegant means to specifically interact with human cells and proteins in order to colonize, survive and the evade host immune […]

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Electrochemical Impedance Modeling and Optimization of Li-Ion Battery Utility using Active Battery Management System (ActiveBMS)

Lithium ion batteries (LIBs) are considered the top candidates among electrochemical energy storage systems (ESS) due to their high energy density which has triggered the growth market of popular devices such as cell phones, computers, electric vehicles (EV) etc. As ESS, LIBs are continuously charged and discharged during their utility. The charge/discharge cycle is known […]

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Electrochemical Impedance Modeling and Optimization of Li-Ion Battery Utility using Active Battery Management System (ActiveBMS) – Year two

In the last decade, lithium-ion batteries (LIB) have become the most popular power sources for consumer devices, telecommunication, energy storage systems, as well as electric vehicles. This type of batteries is indispensable in maintain our modern society. GBatteries have developed an active battery management system (ActiveBMS), which hinders LIB degradation mechanisms, such as the anode […]

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Microfabrication of biosensor for detection of fluid leakages in post-operative complications

With every surgery, there is always a risk that a post-operative complication could occur. NERv Technology Inc. is developing a disruptive solution to post-operative complications. NERv is developing an implantable biochip with multiple biosensors capable of detecting post-operative complications in real-time. NERv has developed a macro-prototype capable of detecting internal bleeding and the leakage of […]

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Development and Evaluation of a Life Threatening Infections Point-of-Care Triage Test for the Fionet System

Febrile syndromes are among the most common causes of global illness accounting for approximately two billion episodes annually. However, most infections are self-limited and only rarely do they progress to critical illness. Our current inability to rapidly identify the small proportion of individuals who will progress to life-threatening infections (LTIs) is a major barrier to […]

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Sustainable production of engineered wood products in Northwestern Ontario: Developing harmonized decision models and standards for local materials

The global demand for engineered wood products (EWP) is increasing and in the last two decades, timber has captured substantial market shares from the mineral-based solid construction materials, particularly in the construction of residential and non-residential buildings. Although, the production of glue laminated timber (Glulam) and cross laminated timber (CLT) engineered wood products has been […]

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iCity Urban Informatics for Sustainable Metropolitan Growth

The visualization/decision support work encompassed by this application addresses key elements of the upgrade path for that strategic part of IBM Canada’s smarter cities product and service portfolio– as urban transport systems evolve, their escalating complexity requires more advanced visualization tools and practices. The specific project proposed for development within the MITACS brief is:• development […]

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Towards a sustainable anti-biofilm technology based on natural materials

Biofilms, surface-adherent microbial populations with enhanced tolerance to antibiotics and disinfectants, are widely-known contamination sources in environmental, industrial and medical settings. Novel approaches for the prevention and remediation of biofilms using nontoxic materials are urgently required. Interestingly, natural polysaccharides and nanopowders have anti-biofilm properties. We will develop a sustainable anti-biofilm technology using PhytoSpherix™ (Mirexus), a […]

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Understanding the Impact of Fontan Circulatory Repair on Brain Blood Flow Health

Children born with an absent or ineffective right or left ventricle (single ventricle) have a low life expectancy and will undergo at least three surgical procedures ultimately leading to the Fontan Procedure (FP), which allows blood to travel directly to the lungs (bypassing the heart) to become oxygenated. Adolescent FP-patients indicate poor cardiovascular health which […]

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