Expert explanations via video: The key to unlocking scientific journal articles for STEM students?

Scientific research papers are complex, dense, and filled with jargon, so traditionally the valuable knowledge they contain has been accessible to only a handful of experts. SAGE publishing, one of the world’s largest academic publishers, and Dr. Adam Frost, a cognitive neuroscientist, independently created video formats that help scientists directly communicate their discoveries and practices […]

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Analysis of proteome dynamics in single cell reprogramming proceeds

The ability to revert human cells back into a stem cell state, and then reprogram them into new cell fates has unlocked promise for future regenerative therapies. However, we still do not fully understand this reprogramming process and the interaction of proteins that make this happen. Mass spectrometry (or MS; a common technique to study […]

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Analysis of proteome dynamics in single cell reprogramming proceeds – Year two

The ability to revert human cells back into a stem cell state, and then reprogram them into new cell fates has unlocked promise for future regenerative therapies. However, we still do not fully understand this reprogramming process and the interaction of proteins that make this happen. Mass spectrometry (or MS; a common technique to study […]

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Cross-frequency coupling in organoids

By growing stem cells in the right conditions, we are able to create miniature brain tissue structures called organoids. These organoids have many properties that make them similar to adult brains, which makes them a valuable tool to study how brain tissues might be affected by drugs, or how brain diseases like epilepsy can occur. […]

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Functional and structural characterization of clinically relevant amyloid fibrils

Irreversible, progressive, and incurable neurodegenerative diseases, such as Alzheimer’s disease (AD) or Parkinson’s disease (PD), constitute severe challenges for the modern and, in particular, for the healthcare system. Recent reports suggest that worldwide >50 Mio. people and >10 Mio. people are living with AD or PD, respectively. Both diseases are related to protein misfolding and […]

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Examination of Foundations and Disbursement Quota in Canada

The purpose of this project is to provide a study of charitable spending by members of Philanthropic Foundations Canada, document the historical impacts brought about by changes to Canada’s disbursement quota (DQ) policy, and recommend changes to the T3010 form. The intern will lead knowledge generation in the form of member engagement, issue briefs, and […]

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The Effect of Droplet Size on Automotive Paint Colour

Spray painting in the automotive manufacturing industry is an extremely difficult technical challenge. Approximately 25% of cars coming off the assembly line must be reworked or scrapped due to a poor paint job. Previous research has shown that the droplet size distribution of the paint being applied to the car is important for the final […]

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Biosurfactants production by fermentation

The proposed project is a collaboration between InnuScience and researchers in the Chemical and Biochemical Engineering Department at Western University. InnuScience uses biotechnology to replace harmful chemicals, eliminate waste, and deliver sustainable cleaning solutions for the cleaning industry. This research collaboration will experimentally optimize the production of biosurfactants by microorganisms via fermentation pathways, focusing on […]

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Negotiating Resource Production, Conservation and Recreation Values in Canadian Wild Food Forest Habitats

Commercial sourcing of wild foods, such as chanterelle mushrooms or wild blueberries, often requires accessing forests with competing uses. They might also be timberlands for conventional forestry, or parks for recreation or conservation. The conflicts that result illustrate how nature and natural resources are valued in different ways in different worlds: by forest managers or […]

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Pharmacodynamic distribution of docetaxel andcabazitaxel in prostate cancer xenografts, and evaluation of pantoprazole to enhance their activity

Chemotherapy drugs target and kill rapidly-dividing cells located closest to blood vessels, but do not penetrate deep into the tumor. Limited drug distribution in tumors is an important cause of drug resistance. A method to increase tumor drug delivery and combat resistance is the subject of this proposal. To counteract chemotherapy resistance, the use of […]

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Learning to Predict Grasp Outcomes

With the growing importance of ecommerce, automated warehousing has gained much interest. A crucial component of such system is a robotic arm or a similar device that allows to grasp, pick up and sort items with complex shapes and in cluttered conditions. We will be working on improving such system, so that online delivery can […]

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