Affine Multivariate GARCH Models

The objective of the proposed research program is to develop a flexible and unified multivariate framework for modeling the returns of financial assets. The program is innovative since it establishes closed-form formulas for an efficient and reliable calculation of risk measures and derivative prices. For financial institutions and government regulators, who are performing pricing and […]

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Biosensor for Detecting Pharmaceutical Residues in Water

The intention of this research project is to detect pharmaceutical agents in water systems, specifically carbamazepine, ciprofloxacin, and diclofenac. These substances present an issue as they compromise the water quality and have low removal rates from conventional water treatments. The use of nanotechnology in biosensors holds the promise of high sensitivity and miniaturization. Here the […]

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Graphene Oxide Langmuir Blodgett (GO-LB) Functional Thin Films

The aim of this project is to utilize the Langmuir Blodgett (LB) deposition technique at the University of Waterloo to form uniform thin films layers of PAni nanocomposites layers. Successful production of thin film PAni nanofibers will allow research into laser writing and the fabrication and testing of simple proof-of-principle flexible sensor devices. This will […]

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Costs of fluoroquinolone resistance in clinical E. coli: a potential explanation for similarities in resistance between the UK and Canada

Antibiotic resistance is one of the biggest challenges faced by modern medicine. Countries operating public healthcare systems need to effectively treat patients while practising responsible antibiotic stewardship. The rising prevalence of resistance means, however, that many current first-line antibiotics are becoming ineffective. In particular, resistance to the the fluoroquinolones, a broad-spectrum class of antibiotics, is […]

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Tetraquarks and Quantum Computing

We will perform a computational calculation to determine the properties of a proposed, currently unobserved type of particle called a tetraquark, within our current understanding of particle physics. This will allow experimentalists to search for such particles, and provide tests of our theory (Quantum Chromodynamics), which we currently find to be in agreement with observations. […]

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Detection of enumeration attacks in cloud environments using infrastructure log data

Most computer services nowadays are provided in cloud environments. Inevitably, every individual needs to use these environments when they have to use computer services. Considering cyber threats in the cloud infrastructure, security and privacy conservation of one is really challenging. Out of date techniques are no more executable in these infrastructures. However, machine learning algorithms […]

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Scaling Security Architecture

Security has become increasingly important as cyberattacks are more prominent. Despite advances in security technologies there’s still a need for a new security architecture that is simply adaptable and scalable to different and evolving security requirements of various organizations. This project will study the latest technologies and solutions in the field of Cybersecurity that are […]

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Technologies of Self: The commercial pocket diary in Canada, c.1780-1890

The commercial pocket diary has been one of the most common ways in which people have recorded their lives over the past two and a half centuries. Yet as a hybrid genre it has often fallen through the net of our historical enquiries. My project will research the importation and production of pocket diaries in […]

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‘Assembling and investigating Tl-201 radiolabelled texaphyrin nanoparticles targeted to prostate cancer cells for Auger electron radiotherapy’

Thallium-201 (Tl-201) is mostly known to clinicians from its previous use in diagnostic imaging. However, this radionuclide is also a potent Auger electron emitter, releasing around 21 short range, low energy electrons per decay. Auger electron emitters have a potential in targeted treatment of small tumours due to localised energy transfer. So far, Tl-201 therapeutic […]

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Sleep and circadian rhythms phenotyping in high-risk bipolar offspring

Bipolar disorder (BD) is a chronic psychiatric disorder with peak age of onset between 15 and 25 years. In clinical practice it takes over a decade from initial symptom presentation to accurate diagnosis, with such delays being linked to a range of adverse consequences. Therefore, finding early markers of vulnerability is essential. Familial history (i.e. […]

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