Extensive research has been conducted for the computational analysis of mass spectrometry based proteomics data, however most of the traditional computational approaches take the assumption that the acquired spectra are generated from the fragmentation of a single precursor and the peptide is simply a linear sequence of amino acid residues. This ubiquitous assumption is impeding […]

The uGPS Rapid Mapper™ is a laser system mounted on a mining vehicle which acquires 3D images of tunnels in underground mines. Currently, engineers use the images for mine design and operations. This research project will create two new applications for the images acquired by the system: mapping of the geology of the tunnel walls […]

Customized image sensors will be designed by EnviroSen specifically for advanced microscopes used in biomedical imaging. The goal is to develop image sensors with improved efficiency, image resolution and speed compared to existing technologies for novel microscopes for fluorescence lifetime imaging. The McMaster Biophotonics group has recently developed a novel microscope that is capable of […]

Detecting subtle chemical and physical changes occurring at the early stages of chronic disease and many other infectious diseases caused by harmful bacteria is still a challenge, as ultra-sensitive sensors with large signal-to-noise-ratio are required to detect them. We recently explored new ways to enhance the sensitivity of magnetic nano-sensors and theoretically demonstrated that under […]

Detecting subtle chemical and physical changes occurring at the early stages of chronic disease and many other infectious diseases caused by harmful bacteria is still a challenge, as ultra-sensitive sensors with large signal-to-noise-ratio are required to detect them. We recently explored new ways to enhance the sensitivity of magnetic nano-sensors and theoretically demonstrated that under […]

Reliable communication over wireless channels has been an active research area for decades. By employing multiple transmit and receive antennas, multiple-input multiple-output (MIMO) systems increase the capacity of a wireless channel, bringing significant gain over single-input single-output (SISO) systems. One of the main tools to achieve the improved capacity are error correction codes. During the […]

Membrane proteins such as ion channels, transporters or G-protein coupled receptors (GPCRs) are excellent but difficult drug targets involved in a large number of life-threatening diseases and conditions. These proteins, over-expressed and essential for disease onset and progression, are naturally targeted by toxins from venomous organisms. During evolution, these toxins have been optimized to efficiently […]

Governments around the globe are trying new approaches to solving complex social problems. They are increasingly moving away from the direct provision of social services towards more collaborative partnerships with the private sector. Pay-for-success, also known as pay-for-performance or Social Impact Bonds, is a method for engaging the private sector that has been gaining attention […]

The aim of The Ontario HIV Treatment Network (OHTN) is to help combat the spread of HIV by supporting, conducting, and sharing the best research possible. This project will involve a novel analysis incorporating focus groups with front-line service providers and key informants to help determine the factors that most influence the perception of HIV […]

Today, due in part to changing economic and competitive procurement processes, sole and small as well as some medium sized architectural practices increasingly need to work in consortium in order to competitively bid for medium to large projects of different types. Currently, there does not exist specific guidelines customized for small and medium practices to […]

As manufacturing and resource-based industries face growing challenges, Canada’s future increasingly depends on advances in and sustainability of knowledge organizations. Knowledge-based workers comprise a growing proportion of the workforce today. More often than not, they work in the context of large-scale expert networks, spanning across different disciplines and organizations. They rely on software technologies for […]

This research project is being undertaken in partnership with The Evidence Network Inc. It will extend the company’s scientifically-based method of assessing the impact of innovation support programs to the clean energy innovation sector. To keep this kind of assessment method scientifically sound requires customization for each particular industry. The established methods have been widely […]