Fibroproliferative disorders are a/the leading cause of morbidity and mortality worldwide. A large group of interstitial lung diseases (ILD) can cause progressive scarring of lung tissues, affecting the ability to breathe. Idiopathic Pulmonary Fibrosis (IPF) is one of the major forms of ILD and is characterized by a progressive decline in lung function. Although the […]

Rupture of cerebral aneurysms often leads to mortality or sever morbidity in most cases. Pathogenesis of aneurysms has been attributed to abnormal flow-induced forces that act on the vessel walls. These forces are typically measured by first recreating patient’s aneurysm model from medical images, and, afterwards, using these as input for computational fluid dynamics (CFD) […]

The development of beneficial bacterial inoculant as biopesticide and biofertilizers is directly beneficial to agricultural producers through the preservation and enhancement of crop quality and yield. At present, a limited spectrum of naturally occurring microorganisms have been developed for directed, commercial agricultural applications in Canada. Engage Agro Corp is interested in developing bacterial inoculants with […]

The central goal of this research project is to broaden measurement of school performance across Canada by developing, collecting, and measuring data on six performance indicators as follows: academic achievement, physical health, social-emotional development, creativity, citizenship, and school climate. Having developed competencies in these areas during phase one of the project, the current phase aims […]

Hundreds of thousands of endemically poor children are in need of quality prostheses. Current manual processes of prosthetic production are labour-intensive and slow. Moreover, the World Health Organization (WHO) estimates a shortfall of 40,000 trained prosthetic technicians in low/middle income countries. Without the enhanced mobility provided by prosthetics, these children suffer from a dramatically reduced […]

Breeding tubercles (BTs) are epidermal structures found on the dorsal surface of pectoral fin rays of males bony fish, such as zebrafish. Females do not have BTs on their fins. BTs appear during the sexual maturation of male zebrafish. Males use their fins and BTs for grasping the female to stimulate egg laying. We want […]

Absence seizures are the most common form of epilepsy in children. These patients often experience transient episodes of impaired consciousness, which have an enormous impact on their quality of life. We are proposing to identify the neural substrates for these seizures. These experiments would provide the basis of future experimental studies examining the biological basis […]

The goal of this research is to understand and develop techniques to improve flour performance in bread making, a low margin market which requires some of the tightest flour specifications across all bakery platforms. Standard flour quality testing methods will be compared to more recently developed quality tests as well as experimental methods. The end […]

The NWMO is designing an engineered barrier system to contain and isolate highly radioactive used nuclear fuel from people and the environment in Canada. Used nuclear fuel is hazardous to humans for millennia. The millennia design life of the engineered barrier system necessitates the use of computer models to predict their evolution. The results of […]

Anorexia Nervosa is an eating disorder characterized by exaggerated weight loss, fear of gaining weight, self-depreciation. It mostly affects young women and is most likely have the highest death rate of any other mental illnesses and of many diseases in general. Anorexia is notoriously treatment refractory and the main explanation is the poor understanding of […]

Arsenic (As) is a contaminant found in ecosystems and drinking water throughout the world; it is a potent human carcinogen. Arsenic levels and speciation are controlled by a series of abiotic and microbial processes. Arsenic toxicity depends on its speciation and proper risk management is linked to predicting As speciation in various environmental matrices. Laboratory […]

Clubhouse International, formerly known as International Center for Clubhouse Development (ICCD) is an international non-profit organization that supports the creation of community-based clubhouses. Using a psychosocial rehabilitation approach, clubhouses provide individuals living with mental illness opportunities to successfully live and work in their communities through a variety of programs and services. Progress Place, an accredited […]