Mucoadhesive nanoparticle eye drop drug delivery

Eye diseases, such as dry eye syndrome, affect about 15% of the population. Eye drop formulations are the most common way to treat eye diseases, but patients struggle with the multiple daily applications required and the resulting side effects. Our goal is to develop an eye drop formulation that requires less frequent application using nanoparticle […]

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Robotic Arm Development for Total Automation of the Ignition Quality Tester (IQT™)

A novel diesel fuel Ignition Quality Tester (IQT™) was developed by Advanced Engine Technology Ltd. (AET) to provided fast, precise, and reliable measurements of Cetane number, which can be obtained by measuring the ignition delay from the start of diesel fuel injection to the point of combustion. The current testing system using IQT™ requires extensive […]

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Design and Development of Actuation and Control Systems for the Synchronized Segmentally Interchanging Pulley Transmission System (SSIPTS)

This research project is responsible for the design, development, and experimentation of the actuation and control systems for synchronized segmentally interchanging pulley transmission system, SSIPTS. SSIPTS is a novel variable mechanical transmission that offers the combined benefits of existing transmission systems for both automotive and wind industries. To ensure high reliability at the high speed […]

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The Line that Separates: Identifying High Potential Franchise Systems

The success of franchising relies on individual franchisees’ ability to evaluate and compare diverse franchise systems, prior to making an informed decision as to which franchise system to become a part of. Surprisingly, however, few forward-looking metrics exist for franchisees. I seek to fill this gap through my proposed Mitacs Accelerate internship project. My proposed […]

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Envisioning an International Community: Proletarian Arts in East Asia

This project explores the relation between internationalism and leftist literature in early twentieth century China and East Asia. A study of internationalism amongst leftist movements offers important insights into technologies and strategies for building coalitions across national, linguistic and cultural boundaries. I propose that examining workers organizations and their literary and cultural links to internationalism […]

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Molecular mechanism of action of anti-fibrotic antibodies

Significant advances in technologies related to antibody discovery and development have allowed therapeutic antibodies to become the fastest growing class of biopharmaceuticals over the last 20 years. Northern Biologics is a biotechnology company that seeks to develop therapeutic antibodies for the treatment of cancer and fibrosis. Together with Dr. Jean-Philippe Julien at SickKids (University of […]

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Building on an Innovative Platform: Tuning Guanine Quadruplex Recognition for Anticancer Applications

Beyond the well-known double-stranded helical duplex, DNA can adopt many unusual architectures, including guanine quadruplexes (G4), which in recent years have been implicated in cellular processes that lead to the development of cancer. It has been shown that these processes can be switched off by maintaining the folded quadruplex architecture using chemical compounds known as […]

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Bioconversion process of pretreated source-separated organic waste by simultaneous saccharification and co-fermentation processing approach for ethanol production

In this project, two different “pre-processing” technologies will be used to fractionate lignocellulosic biomass prior feeding it to the fermentation process for ethanol production. These pre-processing technologies are thermal screw press and cellulose organic-solvent-based lignocellulosic fractionation. The efficiency of above mentioned technologies will be evaluated for sugar yields which are important for enzymatic hydrolysis and […]

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Analysis of aircraft landing on non-standard runways

In some parts of the world, airport runways are not constructed and maintained to the standards expected in North America and Western Europe. Aircraft designed for use on smooth runways may not be certifiable when they are operated on rougher runways because the predicted load cases associated with landing and take-off are very different from […]

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Coronary Plaque characterization using Coronary CT Angiography

Coronary artery disease is caused by a build-up of plaque in the heart vessel. If the plaque causes a large amount of blockage, this can restrict the flow of blood to the heart and cause a heart attack. However, certain types of plaque are fragile (vulnerable) and can transform from a non-obstructive to obstructive blockage […]

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Identifying Predictive Learning Analytics for Learner AcademicSuccess.

With the increased capabilities of technology, data plays an increasingly important role in decision-making (Mandinach & Gummer, 2013; McAfee & Brynjolfsson, 2012) and small and medium-sized enterprises (SME) now require employees to use data to inform practice (Earl & Seashore Louis, 2013; Lohr, 2012). Furthermore, harnessing big data and predictive analytics has transformed many industries, […]

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