Towards Clinical Use of Whole Genome Sequencing based Tests in a Clinical Setting

Using genomics in clinical care has the potential to treat patients more efficiently. There have been a number of recent discoveries of genomic assays that can guide treatment. However, most genomic data is generated in a research setting and useful health data only in a clinical setting. Translating potential genomic research into a clinical setting […]

Read More
Optimization of small-scale anaerobic digesters for on-site organic waste processing

Anaerobic digestion (AD) is a microbial process where organic materials (sugars, starches, hemicellulose, etc) are broken down into renewable natural biogas and nutrient-rich biodigestate byproducts (roughly 5-10% solids in water). The performance of AD systems is heavily dependent on careful control of digester conditions, including pH, temperature, and health and proportions of the bacterial populations […]

Read More
Motion and Attenuation Correction for PET/MRI

During a medical imaging exam, patient motion such as breathing, cardiac motion, and random adjustments of the head or body can affect the accuracy of the acquired images. Positron emission tomography (PET) is a powerful medical imaging technology that can detect minute amounts of an injected probe targeting specific tissue processes and diseases. Magnetic resonance […]

Read More
Development of a next-generation in vivo human gene-editing therapeutic platform

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

Read More
Development of a next-generation in vivo human gene-editing therapeutic platform – Year two

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

Read More
Towards creating intelligent heat stress monitoring and management solutions to safeguard health and wellness

The scientific challenge for this research project is to advance our understanding of the impacts of heat stress in heat vulnerable workers and to use this information towards the creation of intelligent heat stress monitoring and management solutions to safeguard health and wellness. Currently, our understanding of the effects of heat exposure on vulnerable individuals […]

Read More
Needs assessment of challenging behaviours in children with Fetal Alcohol Spectrum Disorders (FASD) and coping strategies from the stakeholders’ perspective

The objectives of this project are to determine the behavioural and emotional problems affecting children with FASD and their parents/guardians and to determine the specific services and supports this group requires to deal with the identified challenges. This information will be gathered by telephone interviews of 100 parents/guardians and 30 clinicians. The intern will be […]

Read More
Formulating a novel goat-whey based drink and studying its nutritional and health functions – Year two

This project will create novel goat milk-based products and test their health effects in healthy adults. Interest in goat milk is increasing, mainly due to two market trends: consumers’ new taste trends for niche/ethnic products, and the perception of goat milk having added health properties. Goat milk is perceived as having intestinal anti-inflammatory effects and […]

Read More
Optimizing the placement of Med-El’s BoneBridge implant: image-guided positioning and biomechanical efficiency

Med-El’s BoneBridge implant provides the sensation of sound to hearing-impaired persons. The device’s transducer is surgically implanted in the skull. Key surgical problems are to find a location on the individual patient’s skull that is thick enough to house the transducer and to place and configure the transducer to maximize sound energy transfer to the […]

Read More
Optimizing the placement of Med-El’s BoneBridge implant: image-guided positioning and biomechanical efficiency – Year two

Med-El’s BoneBridge implant provides the sensation of sound to hearing-impaired persons. The device’s transducer is surgically implanted in the skull. Key surgical problems are to find a location on the individual patient’s skull that is thick enough to house the transducer and to place and configure the transducer to maximize sound energy transfer to the […]

Read More