It is not well known that the majority of breast cancer patients do not receive a survival benefit from chemotherapy. Yet, they experience many negative short- and long-term side effects from chemotherapy. This is also the case for other cancers. There is thus a clear, unmet need for a diagnostic tool that can reliably identify […]

While chemotherapy drugs are effective in combating tumour growth in cancer patients, many such drugs permit the development of drug-resistant tumours and progression of the disease. We have observed that several chemotherapy agents induce the degradation of tumour cell ribonucleic acid (RNA) in the laboratory and in cancer patients. We have further shown that this […]

Lubricating oil degradation is a ubiquitous problem in industrial machinery. In general, this process includes the thermal breakdown, oxidation, and polymerization of the oil molecules as they turn into undesirable by-products while the lubricant ages. Primary antioxidants, also known as radical scavengers, are regularly added to the lubricant to remove the initial peroxy and alkyl […]

The goal of neurosurgery are two folds, 1) to achieve maximal resection of the target lesions, but simultaneously 2) minimize damage to adjacent healthy brain tissues. Currently surgeons rely on preoperative images such as Magnetic Resonance Imaging to define tumor boundaries. However, the accuracy of such images decreases intraoperatively due to brain shift. For these […]

The mining industry is looking for technologies that improve sustainability through reducing environmental and energy burdens. In line with this, a program was created between Sudbury Integrated Nickel Operations, a Glencore Company and Laurentian University to prospect for opportunities for making better use of existing non-mineral resources. Interns on the Mitacs program will bioprosepect mine […]

Object tracking using stereo video is a field of research applicable to a large number of applications. However, most proposed methods are complex, and require significant computing resources to be implemented. As a result, the number of applications and environments where object tracking systems can be realistically deployed is limited. The proposed research project aims […]

Default correlation analysis has an important role in asset pricing and credit risk management. Our proposed default model aims to analyze the default correlation for two international companies. In this analysis, we would like to incorporate existing correlation between the stock indices in different countries and study its effect on the default correlation measure. Moreover, […]

Although life expectancy is increasingly associated with the treatment of heart disease and cancer, there has been virtually no improvement in life expectancy for patients with dementia. Dementia has a devastating impact to the patient, family members and society because patients become dependent on family caregivers, who are then less productive in other aspects of […]

Additive manufacturing (AM) is a promising field as a sustainable alternative to traditional manufacturing processes for the aerospace sector because of the potential of low buy-to-fly ratio on materials. Cold spray offers the potential for AM of titanium parts due to its large deposition rates compared with current AM methods. However, some hurdles are found […]

There is a critical need for new therapies for Parkinson’s Disease (PD), a devastating neurodegenerative disease. Current therapies for PD treat disease symptoms, but do not provide a cure. The ability to generate patient brain-derived cells may rapidly advance development of personalized therapies for PD and other incurable neurological disorders. This study will use brain […]

The WHO defines health as “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity”. The holistic nature of this definition provides the basis for an all-encompassing evaluation of health, which is the guiding principle behind health impact assessment (HIA). An emerging area of public concern in […]

Solutions proposed by software engineering researchers are not usually used by practitioners due to the lack of tool support. The research software Dione was developed as a solution to this problem. Dione is a platform agnostic integrated software analytics solution to tackle this problem. We have implemented prediction models for effort estimation and defect prediction […]