Modeling DNA Adducts as Cancer Diagnostic and Therapeutic Markers: Computational Chemistry Studies of the Structure-Function Relationships of DG-C8-A?C Adducts

Recent nucleic acids research has focused on the formation of genotoxic DNA adducts as covalent modifications of DNA that often result from carcinogen exposure; human-made chemicals can also cause DNA damage through bulky DNA adduct formation. DNA adducts are not only markers of carcinogenic exposure but also alter the regulation of oncogene transcription and standard […]

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Development and experimental study of a vibration controller for a robotic system interfaced with machining operations.

Robotic arms are used extensively in machining applications due to a large working envelope and easy access to restricted areas. However, low stiffness of the robot arm caused by joint flexibility introduces additional degrees-of-freedom and vibration modes, which leads to the deterioration of positioning performance. To attenuate these induced motion tracking errors and vibrations, this […]

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Pricing and Diversification of Flood Risk in Canada

Flood is the single most important natural hazard in Canada. Since 2015, private (overland) flood insurance coverage is gradually being offered to Canadian homeowners and demand for such protection is on the rise in Canada and elsewhere. For the product to be viable to the insurers and to the customers in the long term, flood […]

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Productivity Tracking and Analysis of Earthmoving Operations

Monitoring and control earthmoving operations such as highways and dams construction; require the collection of large amounts of data. Collecting this data manually is time-consuming and it lacks accuracy, so there is a necessity for using automated data collection systems in such operations. Most of nowadays available data acquisition systems are costly back boxes, where […]

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Development of a business model to plastic packaging waste management: the case of the Montreal Metropolitan Community (MMC)

“By being moldable, durable, light, and inexpensive plastic packaging has seen a rapid growth in the use and its disposal is becoming a planetary challenge. Besides sustainable production and consumption globalized trade in waste plastics represents a significant option towards a circular economy. China, who so far represented the greatest importer of this material, recently […]

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Development of a business model to plastic packaging waste management: the case of the Montreal Metropolitan Community (MMC) – Year two

“By being moldable, durable, light, and inexpensive plastic packaging has seen a rapid growth in the use and its disposal is becoming a planetary challenge. Besides sustainable production and consumption globalized trade in waste plastics represents a significant option towards a circular economy. China, who so far represented the greatest importer of this material, recently […]

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Optimization and GMP (Good Manufacturing Practices) translation of GLIDE (Guided Lymphocyte Immunopeptide Derived Expansion) manufacturing process

Leukemia, lymphoma and other forms of blood cancers are still largely diagnosed every year in Canada. These diseases constitute the second leading cause of cancer related death in young adults and the sixth in adult. The five-year survival rates still range between 42% and 85%. Currently, the main treatment is a stem cell transplantation which […]

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Couplage de scénarios d’évolution du territoire à des scénarios climatiques pour le calcul de l’évapotranspiration future spatialisée au Québec méridional — Application de la télédétection –

La recharge des eaux souterraines est le paramètre clef dans la gestion intégrée et durable des ressources en eau souterraine puisqu’elle définit leur renouvellement. Non observable directement, elle correspond à la part des précipitations qui ne s’est pas évaporée et n’a pas été consommée par les plantes (évapotranspiration – ET) ou n’a pas ruisselé. Une […]

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Qualité de l’eau souterraine dans la région des Laurentides et la MRC Les Moulins aux échelles régionale et locale

Ce projet vise à caractériser la qualité de l’eau souterraine de la région des Laurentides et de la MRC Les Moulins. Près de 400 puits seront échantillonnés pour faire l’analyse de 39 composés chimiques incluant les ions majeurs et mineurs (dont les nitrates), la bactériologie, 47 pesticides et 16 composés pharmaceutiques et de soins personnels. […]

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Au-delà des aspects opérationnels, quels sont les enjeux stratégiques de l’Industrie 4.0 sur les donneurs d’ordres du secteur aéronautique??

Actuellement, l’avènement de l’Industrie 4.0 constitue un incontournable pour les entreprises. L’arrimage entre le monde cyberphysique et la pensée stratégique comportent son lot d’opportunités et de défis. De ce fait, ceux-ci ont un impact majeur sur la stratégie organisationnelle touchant l’ensemble des choix et mesures nécessaire à la discipline et à l’atteinte des objectifs. À […]

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