Optimized use of UM171 and derived molecules for the next generation of genetically engineered blood stem cell grafts in high-risk leukemia therapy.

Hematopoietic stem cells (HSCs) have the ability to reconstitute hematopoiesis by giving rise to all blood lineages without exhaustion. Despite the widespread clinical application of HSCs, the success of HSC transplantations relies mainly on the availability of suitable donors and adequate grafts. Obtaining high-quantity and quality hematopoietic grafts for curing hematological and non-hematological diseases remains […]

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High-throughput linguistic content comparison and sentiment analysis

Scrawlr is a platform for unconstrained, global interaction with all internet content and users. Scrawlr allows for user evaluation and unconstrained classification of any Scrawlr-hosted or non-Scrawlr content. For non- Scrawlr content, this evaluation and classification allowance will be first at the URL level but will subsequently be provided at the individual content component level. […]

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Optimization of Isolation and Purification of the Microbe-to-Plant Signal Bacillin 20 from Bacillus thuringiensis

Plants are always associated with a well-coordinated and beneficial community of microbes – the phytomicrobiome; this plus the associated plant forms the holobiont, the entity that provides crop yield. There is considerable communication between the phytomicrobiome and the plant, often through signal compounds. Bacillin 20 is a small protein (a peptide) produced by a Bacillus […]

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Stacking Fhb1, photoperiod/anthesis and plant height genes in elite winter wheat lines

Wheat is a major staple food crop. Winter wheat has higher yield potential than spring wheat. Fusarium head blight (FHB), mainly caused by Fusarium graminearum is one of the major diseases of wheat. FHB related traits (visual symptoms, fusarium damaged kernels-FDK and deoxynivalenol-DON) are influenced by multiple genes or quantitative trait loci (QTL) with small […]

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Line of Business Explainability

Current planning/business analytics platforms automate time-consuming manual budgeting, forecasting, and reporting processes to help business users (e.g., financial officer, human resources, merchandising, marketing, or sales) make business decisions. Moreover, end users often use the interactive “what-if” analyses to understand the data from different perspectives and gain insights. However, the current way of presenting the analysis […]

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Développement du dialogue entre les perspectives scientifiques et autochtones sur la forêt boréale

Les Premières Nations sont de plus en plus impliquées dans les projets de recherche qui touchent leur territoire. Or, le développement de compétences en recherche en sciences naturelles au sein des communautés est nécessaire pour assurer une collaboration équitable et harmonieuse avec les institutions de recherche. La recherche proposée sera menée par la Première Nation […]

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Data Amalgamation and Analysis across Agricultural Data Silos

The agriculture industry uses multiple disparate data sources. Examples of these data sources includes different types of sensors like moisture sensors, weather information, intelligent farming equipment like tractors, and grain tracking applications. This project will integrate two data sources into a common hosted platform. Existing software such as Esri, for geospatial data and analytics, PI […]

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Use of bacteriophage-derived lysins in combating multi-drug resistant pathogens that cause bovine respiratory disease

Bovine respiratory disease (BRD) is the most important disease of feedlot cattle, which remains the leading cause of disease-induced economic loss in the Canadian cattle industries. BRD is induced by bacterial pathogens including the Gram-negative (G-) bacteria Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. Even with current prevention and control measures targeting associated pathogens, the […]

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Compliance and effectiveness monitoring of stream barrier remediations on salmonid bearing streams in British Columbia

Over 400,000 culvert stream crossings are present in British Columbia, with many acting as barriers to fish passage. The frequency of culverts on the landscape has made them the leading cause of linear stream habitat fragmentation for salmonids and a restoration priority. Fisheries and Oceans Canada (DFO), the British Columbia Fish Passage Technical Working Group […]

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Monitoring Stress Changes and Microseismic Events in Pillars During Potash Mining

Mining-induced stress in the area around tunnel openings represents a major design consideration in potash mines. In the past, induced stress has been monitored using an array of techniques derived from the hard rock mining industry, one of the key assumptions being linear-elastic deformation behaviour of the rock. When using these methods in a soft […]

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Développement d’une écloserie de homard aux Îles-de-la-Madeleine

La pêche au homard américain est un des principaux moteurs économiques aux Îles-de-la-madeleine. En 2021, les débarquements de ce crustacé ont représenté plus de 60% du total des captures effectuées toutes espèces confondues. Bien que ces chiffres soient plus qu’encourageants pour l’industrie des pêches ainsi que l’économie madelinienne, il convient de demeurer prudent en considérant […]

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Do viral infections cause queen failure?

Honey bee queens are the only reproductive female in a beehive – if a queen dies or is unable to lay eggs then the whole colony will slowly die. A queen’s lifetime reproductive capacity, or fecundity, is imperative for maintaining a strong, healthy colony, but declining queen quality is a growing concern among beekeepers. Beekeepers […]

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