Les spasmes infantiles constituent un syndrome épileptique unique à la petite enfance, caractérisé par des spasmes généralisés avec une régression neurodéveloppementale. Lorsque les spasmes épileptiques résistent aux traitements médicamenteux, des approches chirurgicales doivent être envisagées. Il y a une pénurie de données sur (1) qui sont les candidats idéaux, (2) quand les patients devraient être […]

Lameness is one of the top welfare problems in dairy cattle and is often caused by hoof lesions. The aim of the current project is to develop and validate the use of a topical pain mitigating product to provide analgesia to cattle undergoing hoof-trimming with severe hoof horn lesions. To achieve this objective a topical […]

Malgré les taux élevés de vaccination contre le SRAS-CoV-2 au Canada, le virus continue de circuler activement. De plus, de nombreux variants continuent d’apparaitre fréquemment et sont capables d’infecter les personnes vaccinées. Dans ce projet, nous souhaitons caractériser la réponse immunitaire induite chez des individus qui ont été infectés par un variant après avoir été […]

Ce projet de recherche vise à mieux comprendre l’impact des relations interpersonnelles sur le fonctionnement cognitif. Plus précisément, le projet de recherche porte sur le biais de conformité, considéré par les chercheurs comme responsable de la polarisation des opinions, notamment politiques, et de l’extrémisation des idées dans la société actuelle. Malgré l’influence importante de ce […]

The project aims to improve disease prevention and control by including cognitive variables in dynamic models of disease epidemic. Classical compartmental models of disease dynamics are typically used to explore the extent to which an infectious disease propagates through the population, while cognitive factors such as misinformation and degree of compliance with public health measures […]

Throughout the Covid-19 pandemic, the critical care workforce has been exposed to a multitude of psychological risks, and because of this health care professionals are experiencing unprecedented levels of exhaustion, burnout, anxiety, depression, stress, Post Traumatic Stress Disorder, and moral distress. These psychological effects of the pandemic have led to an increase in workforce turnover. […]

The increasing reliance on protein sources alternatives to meat-based products includes insects, which have not been extensively monitored or analyzed so far. Yet, there is evidence that insect may contain potentially toxic elements (PTEs), such as arsenic, mercury, cadmium and lead. The development of reliable analysis methods is required to monitor the levels of PTEs, […]

Knee osteoarthritis (OA) can present in different ways. The relationships between the symptoms and their causes are mostly unknown, making it difficult to choose the best course of action. Being able to identify various contributor to symptoms would be extremely beneficial to determining the optimal course of treatment. We will develop a system that accounts […]

This project learns from the experience of participants in an eight-week Mind-Body Medicine program (MBM). Mind-Body Medicine (MBM) teaches people how to help themselves by uncovering and engaging their inner resources and building resilience, broadly understood. The eight-week MBM program is delivered through the Iris Centre for Mindfulness, Peace and Healing in Fredericton. The research […]

In multiple sclerosis, the protective coating around nerve cells called myelin and the brain cells that make myelin, called oligodendrocytes, are lost. In addition, research has shown that astrocytes, another type of brain cell, may have a negative impact on recovery in MS. Our project takes on a two-birds-with-one-stone approach to combat MS by delivering […]

The oncogenic kinase AKT1 is a prime therapeutic target, but its function cannot be easily researched as AKT activation in cells requires stimulation of cells with an unspecific growth factor that alters all cellular signaling. I designed a new method to deliver an already activated, phosphorylated AKT1 protein to cells that do not require the […]

Brain metastasis of breast cancer has a very poor prognosis in patients. Treatment options are limited because the blood-brain-barrier prevents drugs from entering the brain. Importantly, we are lacking information on how brain cells are supporting the growth of metastatic breast cancer cells. Using HER2-positive breast cancer cells isolated from a patient brain metastasis the […]