L’origine évolutive des dihydrofolate reductases de type B

Les enzymes dihydrofolate réductases de type B (DfrB), identifiées pour la première fois dans les années 1970, confèrent une forte résistance à l’antibiotique triméthoprime. Depuis, ces enzymes ont été étudiées en détail de manière enzymatique et biophysique. Alors que ces enzymes sont connues depuis cinquante ans, leur origine évolutive demeure un mystère. Ainsi, cette recherche […]

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Frailty risk detection from primary care electronic medical records

Older adults with frailty are at high-risk of declines in their health and do not bounce back as well as their non-frail counterparts. These patients are among the highest users of health care because they end up in crises and go to emergency, are hospitalized, or die. But, if frailty is detected and managed earlier, […]

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Innovations in Research & Service Design: Developing a “Youth Collaboration Framework ” with homeless and at-risk youth at Operation Come Home

This research study will allow PhD candidate Charlotte Smith, mentored by Dr. Malenfant and Dr. Spencer, to engage a team of at-risk and homeless youth in a collaborative study by working closely with the community partner, Operation Come Home. Charlotte and Malenfant will provide 5 youth with research training including methods, ethics and more. The […]

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Bridging Cultural Understanding in Mental Health Support for Newcomers

Sara Riel wants to improve organizational support to newcomers to Manitoba with their mental health needs. “Past studies suggest that immigrants, generally, arrive in Canada with better self-perceived mental health than Canadians, but it declines after a period of time (Salami, 2017).” This has deteriorated further during the Pandemic. (Stats Can). There are linguistic and […]

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Obesity and Macrovascular Complications of the Heart and Kidneys: the Emerging Role of Genetics to Predict Risk and Treatment Outcomes

Globally, obesity continues to be a growing public health challenge and has been associated with cardiometabolic diseases including cardiovascular disease, type 2 diabetes and chronic kidney disease. Current strategies aimed at reducing these cardiometabolic diseases include treatments aimed at controlling hypertension, insulin resistance and dyslipidemia. In more severe cases, bariatric surgery is used to decrease […]

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Mimicking medial-knee brace gait using PCA and biofeedback

Knee osteoarthritis is a disabling disease affecting millions of people worldwide. Knee braces have been adopted as a treatment strategy to help manage osteoarthritis pain. These braces apply a force to the knee, which, in theory, reduces the joint loads in the knee. They also however change the way people walk, which can also reduce […]

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Social and Community Economic Development Planning in Toronto

“Social and Community Economic Development Planning” is a BSI project is comprised of four internships associated with four non-profit partner organizations engaged in organizing, advocacy and planning for affordable housing and community supports in low-income, racialized and marginalized neighborhoods. The shared context for this work is the ongoing gentrification in downtown Toronto , coupled with […]

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Enhancing adherence to online PBC wellness programming

Online wellness programming offers a promising avenue to positively influence the mental well-being of older adults with chronic conditions in a manner that is accessible and acceptable. This project aims to build on our collaborative relationship with the Canadian PBC Society to iteratively refine an online wellness program to the unique needs of individuals with […]

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Evaluating New Methods for Monitoring Cognitive Health

Copeman Healthcare Centre is engaged in a multi-year research and development program in the area of cognitive health. Cognitive health is a surrogate marker for brain health. All other technologies, such as biomarkers, electrophysiology, structural brain imaging, and functional brain imaging attempt to measure damage to the brain. Moreover, these technologies do not measure or […]

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« Implanter la fonction de l’Intervenant en Soins Spirituels à la Maison en soins palliatifs St-Raphaël à Montréal »

La Maison St-Raphaël porte un centre de soins palliatifs et un centre de jour dans un quartier de Montréal très dense de plus de 360 000 personnes. Forte d’une équipe de professionnels très engagée, cette maison de soins palliatifs accueille sans relâche des personnes vulnérables qui ont besoin d’un accompagnement interdisciplinaire. Le projet actuel consiste […]

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