Drug models describe the relationship between exposure (or pharmacokinetics), response (or pharmacodynamics) for both desired and undesired effects, and individual patient characteristics. In this project, drug models will be used to propose an integrated dose adaption strategy for cancer treatment. This strategy has a particular clinical value for our partner (InVentiv Health Clinical, a Contract […]

The intestinal tract is at the centre of animal production because it is responsible for absorption of nutrients and is the place of action of important pathogens. The characterization of bacterial communities has been revolutionized by the development of DNA sequencing technologies, which allowed the discovery of many new species and a better understanding of […]

Le sujet a l’etude dans ce projet est le joint de cuivre flexible. Ces joints assurent une connexion electrique entre des conducteurs. Certains fabricants utilisent aujourd’hui ces joints flexibles dans les alternateurs pour faire les connexions entre les poles du rotor pour l’inducteur. Le dimensionnement de ces joints flexibles s’effectue avec une approche conservatrice compte […]

Electrochemical sensors for monitoring dissolved oxygen levels are commonplace in industrial, research and regulatory labs. The industrial partner?s commercialized device is capable of real-time monitoring of O2 at parts-per-billion levels but is interested in reformulating the electrode materials to remove heavy metals, thereby minimizing negative environmental impact and ensuring sustainability of the technology. This project […]

Les puces microfluidiques ont montré beaucoup de potentiel pour la culture d’échantillons de tumeurs à l’extérieur du corps (ex vivo). En conservant la viabilité des tumeurs jusqu’à 15 jours, elles ouvrent la voie vers des tests prédictifs de la réponse des patients au traitement avant même leur prescription. Toutefois, pour que la technologie soit commercialisable, […]

Le projet de recherche a pour but de faire progresser les outils techniques de la construction hors site (CHS) de structures modulaires en ossature de bois. Utilisant une méthodologie appelée recherche-action, le stagiaire devra élaborer un prototype fonctionnel d’une plateforme numérique spécifique pour l’industrie de la construction afin de faciliter la CHS et d’améliorer son […]

There is growing evidence that outcomes after colorectal surgery are improved with the use of perioperative interventions combined into an enhanced recovery program (ERP). Encouraging patients to achieve specific daily nutrition and mobilization goals postoperatively is an important aspect of ERPs; however, it is not known whether the achievement of these goals needs to be […]

Recent environmental concerns and legislations over the use of lead are driving the microelectronics industry towards intensive search for lead free solder alloys in electronic packaging. Among many lead free solders, Sn-Cu-Ag system has been regarded as the most promising and attractive candidate alloy system for the conventional Sn-Pb solder alloys, owing to its wettability […]

Ditch Labs is a medical technology company developing a new treatment for smoking cessation. The objective of this research project is to understand how nicotine delivered by a novel electronic nicotine deliver system travels through the body from its absorption to its excretion. The study is important because it will allow Ditch Labs to select […]

Atmospheric corrosion, commonly known as weathering is among the leading causes of infrastructure degradation. The extent of atmospheric corrosion becomes more concerning when it triggers localized and non-linear metal loss rates. One such scenario is the localized corrosion at the flanged connections in piping, pipeline, and equipment for hydrocarbon industry and even utility sectors. As […]

Ce projet collaboratif vise à développer une ligne de production automatisée pour le moulage de pièces en matériaux composites pour l’industrie automobile. Le procédé de fabrication développé par la société sera doté d’un système de contrôle automatisé Industrie 4.0 ayant l’avantage d’une inter connectivité des équipements de fabrication, ce qui permettra un suivi en ligne […]

Our project will determine needs and barriers to use of a water data collaboration platform use by diverse stakeholders, which include watershed groups (Indigenous communities, sub-basin organizations, science classes, citizen science coalitions), industry stakeholders (irrigation districts, reservoir operators) and potentially government agencies charged with creating and implementing water management policy. To understand barriers to platform […]