Expanding the capabilities of a neurosurgery software platform to provide clinical solutions for advanced spinal cord imaging and intra-operative guidance

Pathologic changes that occur in the cervical spinal cord as a result of injury and disease are not well characterized with current clinical imaging techniques. Synaptive Medical has recently developed a suite of innovative medical imaging products focused on the brain and image-guided neurosurgery. They are interested in investigating the potential application of these technologies […]

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Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic […]

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Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies – Year two

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic […]

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Acoustically derived indicators of demersal and forage species productivity in the Strait of Georgia, and their link to the survival of juvenile salmon – Year two

With a rich acoustic dataset available in the Strait of Georgia (SoG), we propose this research to develop a series of acoustic indicators of productivity for forage (e.g. Pacific herring, mesopelagic fish, euphausiids, zooplankton and ichthyoplankton) and semi-demersal (e.g. Pacific hake and walleye pollock) species within the SoG by using robust multi-frequency techniques. Along with […]

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Leader competencies and character: A novel approach to leader development

Historically, executive coaching programs have focused on developing a leader’s competencies. More recently, the character of leaders has received increased attention in the media and in research literature. This can be attributed to the financial crisis of 2008-2009, which shined a spotlight on unethical decision-making by leaders in organizations. As a result, there is a […]

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Development of Ex-situ Mechanical Durability Tools and Thermo-mechanical Design Curves for Fuel Cell Membranes

Hydrogen powered polymer electrolyte membrane fuel cells (PEMFCs) are a clean energy technology that generates electricity without harmful emissions at the point of use. Current R&D efforts mainly target to commercialize PEMFCs through cost reduction and durability enhancement. The lifetime of PEMFC is limited by the degradation and failure of the polymer electrolyte membrane (PEM). […]

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Development of Ex-situ Mechanical Durability Tools and Thermo-mechanical Design Curves for Fuel Cell Membranes – Year two

Hydrogen powered polymer electrolyte membrane fuel cells (PEMFCs) are a clean energy technology that generates electricity without harmful emissions at the point of use. Current R&D efforts mainly target to commercialize PEMFCs through cost reduction and durability enhancement. The lifetime of PEMFC is limited by the degradation and failure of the polymer electrolyte membrane (PEM). […]

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Identification of copy number variation biomarkers in patients with inflammatory bowel disease

Copy number variations (CNVs) are an important type of structural variation affecting pathogenesis of complex diseases, such as inflammatory bowel disease (IBD). Accurate detection of genomic regions with CNVs is crucial for understanding the etiology of IBD, as these regions contain likely drivers of disease development. Microarray technology provides single-nucleotide resolution genomic data and is […]

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Optical determination of membrane defects and correlation with fuel cell performance and durability – Year two

There is a strong push toward producing fuel cells on a commercial scale. This means a greater focus on production speed and yields with a need to understand the unintended features that arise from larger-scale manufacturing processes. This project requires the set up of state-of-the-art, camera-vision, defect detection equipment to find and collect observed membrane […]

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