Dimensionality, performance, and stress testing of multifactor equity models

A global multi-factor equity model had been previously developed. It employs a group of sector indices for different regions using Dow Jones, MSCI, and indices of local stock exchanges. PCA is used to produce independent factor variables, and then specific equities are regressed against the PCA factors. By transforming factors back into real world variables […]

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The I-Score Study: The development and validation of a patient-reported measure of antiretroviral therapy’s interference with life.

Many HIV-positive persons on HIV medication have trouble taking this medication as prescribed by their doctor (treatment adherence). This threatens the long-term ability of the drugs to preserve a patient’s health. For 1 in 5 in Canada, their medication does not work, in part because of adherence problems. Furthermore, doctors and their HIV-positive patients do […]

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Bridging Two Worlds: Culturally Responsive Career Development Programs and Services to Meet the Needs of Newcomer and Refugee Children in Canada

This three-year research program investigates schools and communities in Calgary, Winnipeg, Charlottetown and St. John’s to learn about their shared and disparate approaches to career development for refugee and newcomer children. This knowledge will prepare counsellors and teachers who provide career development programs and services and it will create stronger networks between community partners, universities […]

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Apelinergic system as a promising target for myocardialdysfunction and shock

Cardiovascular disease and sepsis are two of the biggest public health problems in North America. Increasing evidence further suggests they are linked. Recent studies in human healthy volunteers and in chronic heart failure patients have highlighted the apelin system as a potential target for drug development. We therefore propose to fully validate pre-clinically the potential […]

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Modeling User Behaviour Over Time from Chat Messages

As online communication among children and young adults grows in popularity, concerns about online safety are receiving vast attention. The Two Hat Security (2HS) company has a rule-based filtering system to detect malicious chat messages and identify abusive users. The proposed project will improve the predictions of the trustworthiness (trust-level) of the users which can […]

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Role of 5alpha-Dihydrotestosterone and Androgen Receptor in Estrogen Receptor-Positive Breast Cancer

Breast cancer is the most frequent cancer affecting women, with 1 in 9 Canadian females expected to develop the disease in their lifetime. About 90% of estrogen receptor (ER)-positive breast cancers express androgen receptor (AR). Recent results in our laboratory demonstrated that the inactivation of 5alpha-dihydrotestosterone (DHT), the most potent androgen, contributes to estrogen-dependent breast […]

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Development of a Patient Aid for Grading of Acne Severity and a Comprehensive Acne Quality of Life Instrument (CompAQ) for Acne Patients

The overall objective of this work is to gain a better understanding of the experience of patients living with acne and how to support their decision making process in terms of acne treatment options. This research will investigate issues surrounding how patients understand how to accurately determine the severity of their acne and the treatment […]

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Spelling Correction for Improved Detection of Malicious Chat Messages

Cyberbullying, sexting, profanity and other forms of malicious chat messages have become increasingly common in online virtual worlds and social networks that are used by children and teenagers. These conversations are dangerous to children. The partner organization has already implemented a rule based filtering system to filter out malicious messages. However, not all the malicious […]

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Development of new approaches to promote proliferation of insulin producing pancreatic ?-cells in diabetic patients

Reduced number of insulin producing ?-cells in pancreas due to increased ?-cell death is a key defect in diabetes that eventually leads to elevated blood glucose levels and life-time treatment with glucose lowering drugs or daily insulin injections. Thus, finding therapeutic approaches to prevent the decrease in the number of insulin producing ?-cells in diabetic […]

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Defining SDN protocols to enable Orchestration of Service Provision across Multiple Optical Transport Networks

The primary goal of the intern project is to research and propose implementations that enable streamlining the APP (application layer) interface to flow through the SDN layered model. The target solution would enable a SDN-standardized approach of handling the APP communication with the data plane. It involves developing an Application plug-in for the Open Day […]

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