This research aims to develop a novel method for RNA-based regulation of gene expression, which would provide an alternative to existing popular and patented methods. The proposed method utilizes computationally designed trans-acting hammerhead ribozymes (taHHRzs), which would cleave a reporter gene transcript, unless special ‘anti-cleaver’ RNAs bind to a designated part of the taHHRz. This […]

Improving driving safety is an ongoing challenge with far reaching consequences for Canadians. One method of improving driving safety is by improving driver performance with hazard perception training. Hazard perception is a driver’s ability to anticipate dangers in the road environment and is predictive of the likelihood of being in a crash. Several countries including […]

Pour résoudre une problématique liée à l’analyse d’images en temps réel, Lapalme Gestion Conception Mécanique recherche un algorithme d’intelligence artificielle qui soit performant dans un contexte de tâches agricoles. Lors d’un précédent projet, nous avons identifié plusieurs modèles prometteurs. Nous visons maintenant à pousser les performances des modèles tout en limitant l’effort d’annotation de nouvelles […]

This project investigates the cost effectiveness of applying product line techniques to the development of the common elements of certain types of video games. Approximately ten games will be analyzed to identify those parts that are used by most of the games. Those commonly used parts will then be re-engineered to make them more generic […]

Une augmentation des taux de détresse et des symptômes de dépression et d’anxiété chez l’ensemble de la population a été remarquée au cours des dernières années et en particulier chez les travailleur.se.s. Bien que plusieurs mesures ont été mises à disposition pour aider les gens à surmonter cette période critique (p. ex., des ressources sociales […]

L’industrie viticole au Québec est en pleine expansion avec un intérêt croissant de la population de consommer des produits locaux de qualité. Connu pour ses bienfaits sur la santé humaine notamment grâce à ses propriétés antioxydantes, le vin a largement trouvé sa place sur les tables québécoises. Cependant, les raisins cultivés au Québec manquent souvent […]

Canada has enormous potential to recover renewable energy and chemicals from over 18 million tonnes of waste generated annually while simultaneously reducing greenhouse gas (GHG) emissions associated with landfilling that account for 13% of national methane emissions. The proposed project will develop the fundamental science and technologies needed to realize sustainable waste to chemicals manufacturing […]

To address the urgent problem of climate change, it is important to look for alternatives to fossil fuels. Renewable energy sources, such as solar or wind power, are attractive but are often criticized for being intermittent: the energy produced varies with time of day or season of the year. There is a mismatch between the […]

Incorporating geosynthetic layers on top of the subgrade layer provides more stability and serviceability. That becomes a must when the subgrade layer is classified as a problematic soil. With the traditional method, two layers of geosynthetic are adopted: a geogrid for reinforcement and a geotextile for filtration. Placing these two materials in this manner is […]

La planification de rdv à domicile (infirmières ou pour rdv de techniciens) est complexe. Elle nécessite des compétences géographiques et une connaissance métier de répartiteur. Ce processus prend énormément de ressources. Ce projet vise donc projet à concevoir une méthode de suggestion d’horaire de rendez-vous sans avoir à réoptimiser de lourds emplois du temps.

This project will investigate how software developers work with structured information. It will use information about that interaction to improve tools needed by developers. It will assess whether those tools improve the productivity of software developers. The project will also compare the access patterns of users of business intelligence applications to those of developers to […]

PulseMedica is developing a medical device platform to treat vitreoretinal eye diseases that affect over 500 million people worldwide. Our device consists of a state-of-the-art 3D imaging and surgical platform that allows for comprehensive patient treatment including machine learning based disease detection, surgical planning, surgical treatment, and post-surgery evaluation. This device uses multiple laser-based imaging […]