Optimization of novel antibacterials targeting the ATP synthase of difficult pathogens

The proposed research project aims to develop new class of antibiotics targeting bacterial ATPsynthase for difficult-to-treat bacterial infections, particularly those involving Staphylococcus aureus or Escherichia coli. To do so, one post-doctoral fellow will be recruited in the lab of Pr. P-L Boudreault (Université de Sherbrooke), to work on the synthesis of small molecule analogs. This […]

Read More
Lock-in detection of Raman resonance (LIDORR) in the presence of overwhelming fluorescence

Efforts to sequester atmospheric carbon in soil require effective monitoring methods. Soil water content confounds the conventional application of infrared absorption. Raman spectroscopy contends well with water, but suffers from the overwhelming fluorescence typically encountered in the analysis of soil samples. Here we propose to combine an modulated two-colour illumination scheme with antiphase lock-in detection […]

Read More
Waste Collection / Street Sweeping / Snowplow Route Optimization

A key objective of this project is to develop an advanced routing strategy that can generate optimal routes for curbside waste collection, residential sweeping, and snowplowing services to improve operational efficiency and save overall costs. To achieve this goal, optimal routing models and algorithms will be developed by integrating graphic theory, vehicle routing problem, and […]

Read More
Marketing Analyst – Internship

ALTA Consulting specializes in working with small to mid-size organizations that need assistance with growth strategy and are looking to establish or grow sales and marketing. We help these companies engineer revenue. With this project, we plan to onboard one Master’s in Business Administration student with relevant experience to participate in the ongoing efforts to […]

Read More
Criterium Group – Winter 2022

Criterium Group will support the Energy Client in transforming operations and determining the most sustainable and economic decarbonization technologies to utilize at The Asset. The Asset site has important characteristics that facilitate bridging to the new technological solutions being pursued as well as beneficial infrastructure, integration, and geological attributes that could improve the feasibility and […]

Read More
Synergizing biophysics and AI to identify NASH therapeutics

Fatty liver disease (a.k.a. Non-alcoholic fatty liver disease (NAFLD)) and progressive liver fibrosis are a critical health concern across the world affecting as much as 25% of the world population and have become an enormous health concern leading to liver failure and hepatic carcinoma. There are no established drug regimens for these liver diseases. To […]

Read More
Multi-hazard Risk & Resilience Assessment for Real Asset Decision-Support

High-resolution natural risk analysis of client-specific asset portfolios that supports science-based decision making for asset modernization, upgrade and acquisition & disposal is a crucial part of asset management in the face of major natural hazards and climate change. The interns will work to combine existing insurance catastrophe models and advanced engineering analysis of earthquake, extreme […]

Read More
Development, Design, and Implementation of Low Carbon Concrete Structures

The production of cement contributes to 8% of global CO2 emissions resulting in a pressing need to develop strategies for reducing the use of cement. This research project focuses on reducing cement use by improving structural efficiency. In order to fully understand the behaviour of these efficient structural elements and ensure that they will provide […]

Read More
Moose (Alces alces) winter habitat selection in the Northeast Superior region: comparing ways of knowing and seeking joint solutions using improved forest data

The goal of this research project is to identify where Indigenous Knowledge differs from how the province of Ontario understands and manages winter moose habitat, in order to better protect moose populations in the Northeast Superior region. Additionally, new and improved forest inventory data in the region will be investigated as a potential tool to […]

Read More
Hydrogen Gas – Carbon Microsphere and Graphene Oxide Adsorption/Desorption Analysis for solid state hydrogen storage

Climate Change (CC) mitigation and reduction requires a strong effort to develop and put into use clean energy options that significantly reduce anthropogenic CO2 emissions. In Canada, the transportation sector accounts for 25% of all emissions. Hydrogen fueled vehicles is one option that has a great potential to reduce Canadian and global CO2 fuel emissions. […]

Read More
Impact of the addition of a newly developed bio-resin called Biofusion on the strength of concrete

Concrete—the most common construction material in the world—represents the main component of construction. Aggregate materials normally occupy about 70% of the concrete volume and their production results in excessive emission of carbon dioxide. One potential solution to reduce the carbon dioxide emissions from the construction industry is to use the newly developed bio-resin Biofusion in […]

Read More
Statistical Perspectives on Drug SafetyScreening using Spontaneous Reporting Dataand Electronic Health Records

Screening spontaneous reporting (SR) or electronic health records (EHR) data sets for adverse drug reactions (ADRs) has become an important component of drug safety. Much methodological work has been historically done on SR data, however, novel approaches are continually being suggested which merit critical review. Thus, we will first investigate some of these approaches as […]

Read More