Integrating comparative genomics and Tn-Seq data to uncover genetic interaction networks in pathogenic bacteria

Antibiotic resistance is a rising threat worldwide, making infections increasingly hard to treat. This project aims to tackle this urgent issue by mapping out the hidden genetic relationships within harmful bacteria, including Escherichia coli and related pathogens. By analyzing vast amounts of genetic data, we will identify critical points—called genetic hubs—essential for bacterial survival. Targeting […]

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Human-Centered Design and Regulatory Strategy for a Digital Heart Failure Self-Management Tool

This project involves partnering with a medical device company focused on supporting older adults with heart failure through an innovative self-management software. Key activities include developing comprehensive documentation to support the company’s quality management system, contributing to a usability study to evaluate the software’s real-world impact, and refining the design to ensure it meets both […]

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Evaluation of frass, a waste stream from industrial insect production, as a soil amendment.

Industrial-scale production of insect-derived protein has emerged as a sustainable alternative to wild harvesting or large animal farming. The principal waste product is called frass, which is composed of excrement, larval exoskeletons and microbes. Frass from black soldier fly larvae (BSFL) has plant-growth promoting (PGP) properties and is therefore well positioned as a replacement for […]

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Evaluating Mutational Signatures from Circulating Tumor DNA: A Comparative Analysis with Whole-Genome Sequencing

Cancer leaves behind unique mutation patterns, known as mutational signatures, which provide insights into its origins and potential treatments. Traditionally, these signatures are identified using tumor tissue samples, but obtaining biopsies can be invasive and challenging. A promising alternative is circulating tumor DNA (ctDNA)—small fragments of tumor DNA found in the blood. Liquid biopsies offer […]

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Forecasting Levodopa-Induced Dyskinesia in Human Subjects with Parkinson’s Disease

We have developed a novel data augmentation procedure that significantly enhances machine learning-based classification of different brain imaging scans. Having successfully demonstrated proof-of-concept in a rodent model, we are now expanding this approach to clinical applications in humans. Specifically, we aim to utilize this technology to identify early biomarkers of neurodegenerative diseases, enabling personalized treatment […]

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Emma Lake Environmental Research and Stewardship Internship

Emma Lake is one of many recreational lakes located in the boreal forest of west central Saskatchewan that has experienced increased cultural eutrophication due to increased lake development and urbanization. Cultural eutrophication refers to artificially enhanced nutrient loading associated with shoreline development, vegetation removal, and factors related to sedimentation, increased use of fertilizers, and proliferation […]

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Phytochemical & Clinical Evaluation of Natural Health Products Against Cancer

Substantial research has been implemented to delineate the efficacy, mechanism of action and identification of the medicinal components of natural extracts for clinical use, especially in the field of cancer. This project is aimed at identifying all biologically active components of dandelion root extract (DRE), a natural health product (NHP) that has shown potential as […]

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Scale-up to semi-industrial cultivated fat production

Main Activities Genuine Taste is an innovative biotechnology company focused on producing cultivated fat, a scalable and customizable ingredient for the growing alternative protein industry. We provide high-quality, structured fats that enhance the flavor, texture, aroma, and nutritional profile of plant-based and cultivated meat. Our technology offers a cost-effective alternative to conventional animal fats and […]

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Étude de la croissance des moules

La température de surface des océans a augmenté d’environ 1 °C depuis l’époque préindustrielle, une tendance qui ira en s’accélérant. L’effet probable de ce changement environnemental sur la croissance des mollusques marins sera étudié par le biais de simulations sur ordinateur. Ce travail met en jeu la moule. Nous nous servirons de données sur l’alimentation […]

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Assessment of the neuroprotective effects of a novel natural product derived formulation in a rodent model of Parkinson’s disease

A number of natural products including ginseng, green tea catechins and the essential fatty acids DHA and EPA display neurosupportive and neuroprotective qualities. These bioactive compounds may be useful in preventing various forms of neuronal cell loss, including the degeneration observed in Parkinson’s disease. The industry partner, Neurodyn Life Sciences Inc., has developed a proprietary […]

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Rhythm & Blues Cambridge Black Needs Assessment

Rhythm & Blues Cambridge is leading a Black Needs Assessment Study to identify service gaps, barriers, and opportunities for Black families in Cambridge and across Waterloo Region. As the only Black-led nonprofit service provider in Cambridge, Rhythm & Blues Cambridge is committed to expanding culturally affirming programs, strengthening community partnerships, and advocating for equitable access […]

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