Outdoor air pollution and cancer in Canadian children

Outdoor air pollution is a human carcinogen. This classification is based largely on a series of studies that has shown it increases respiratory cancers in adults. There is more limited evidence that that suggests it increases the risk of childhood cancer. To date, there have been few Canadian studies on this topic, and none that […]

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Reconstitution de la variabilité climatique holocène au centre du Canada à partir des assemblages de chironomes subfossiles

Le climat de la planète se réchauffe rapidement, et les régions boréales du Canada sont parmi les plus touchées. Pour comprendre comment ces forêts réagiront au réchauffement actuel, il est essentiel de connaître comment le climat a évolué dans le passé. Ce projet cherche à reconstituer les variations de température des 13000 dernières années au […]

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Toxicological effects of essential oils on aphids and natural enemies

Chemical insecticides play an important role in global food production, ensuring reliable pest control and high crop yields. However, their intensive use also brings significant challenges—environmental contamination, risks to human health, and the rise of resistant pest populations. Addressing these issues is critical to maintaining both agricultural productivity and sustainability. This project seeks to discover […]

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Studying formation and destabilization mechanisms of pickering emulsions encapsulated with bioactive compounds via confocal/STED microscopy

Bioactive compounds are naturally occurring food components that can promote human health, but they often lose their effectiveness because of problems such as low stability, low solubility, and poor absorption in the body. Encapsulation in emulsions is one promising way to protect these compounds and help them reach their target tissues, but the main limitation […]

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Understanding Counsellors’ Perspectives on the Mental Health and Wellbeing of Farmers: A Descriptive Qualitative Study

SaskAgMatters (SAM) Mental Health Network Inc. is a support network created to offer a farm-culture friendly mental health support system for Saskatchewan (SK) Agricultural Producers (hereafter collectively called ‘farmers’). SAM offers six free counselling sessions with registered mental health professionals who have backgrounds in agriculture. SAM’s counsellors will be invited to semi-structured interviews focusing on […]

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Deciphering the role of plant mitochondrial alternative oxidase (mtAOX) isoforms by protein carbonylation profiling

Plant cells naturally express enzymes that remove the reactive oxygen species (ROS) or prevent their production to a detrimental level under stress conditions. One such protective enzyme is the alternative oxidase enzyme (AOX) that is unique to plants among all other eukaryotes. There exist five AOX enzyme isoforms, AOX1a, AOX1b, AOX1c, AOX1d and AOX2, in […]

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Enquête sur la pratique ostéopathique au Canada: Une analyse transversale

Au Canada, environ 8 millions de personnes souffrent ou souffriront de douleur chronique, un nombre en hausse avec le vieillissement de la population. L’ostéopathie, basée sur des techniques manuelles, vise à soulager ces douleurs et améliorer la fonction. Toutefois, l’ostéopathie n’est pas réglementée au Canada, et on en sait peu sur les ostéopathes et leurs […]

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Designing cross-species-reactive compact promoters for targeting specific cell types in the body

The interns will first conduct market research to determine the demands of the current life sciences industry, including pharmaceutical companies, gene therapy development companies, and companies that offer transgenic animal models. With this data, the interns will work together using a proprietary machine-learning algorithm from Re:Pair Genomics to design a catalog of 5-10 different compact, […]

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Glycoproteomic analysis of erythrocytes and PBMCs

The healthcare system relies heavily on blood and blood products for a large variety of life-saving treatments. However, blood products are perishable and have short shelf lives. Given the continuous demand for these products, this issue must be addressed. As blood is stored, the profile of cell surface sugars, known as glycans, has been shown […]

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Emergency Department (ED) Wait Times at Waterloo Regional Health Network (WRHN) – ED Challenge – PhD Intern

Despite numerous system interventions, emergency department (ED) wait times at Waterloo Regional Health Network (WRHN) remain a critical challenge. As part of an Innovation Partnership Procurement by Co-Design initiative led jointly with the University of Waterloo under the CareNext Coalition, WRHN is now engaging vendors and internal stakeholders to co-develop novel interventions that improve patient […]

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Fine-Tune AbilityGPT to Create Dual-Specific Therapeutic Antibodies

We propose to use AI to generate tuned antibodies that reduce side effects using GPT models fine-tuned from the AbilityGPT base language models created in the previous project. Starting with the AbilityGPT models based on several sizes, fine tune the models using sequences known to be active for selected targets. These may be selected from […]

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Development of a unique natural product catalogue through chemical characterization of Canadian wild plants

The proposed research aims to investigate and chemically characterize Canadian wild plant species. Natural products from plants are valuable to many industries and for promoting health and wellness. Certain plants that flourish under the conditions found in the Canadian prairies are likely to be rich in valuable chemical compounds. The research will be conducted by […]

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