Use of sourdough to improve the color of durum wheat pasta

Wheat carotenoids give durum wheat pasta a light yellow color. Wheat lipoxygenase oxidizes flour carotenoids and further loss of carotenoids is caused by extrusion of pasta. Because bright yellow pasta is preferred by consumers, oxidation of carotenoids during extrusion impairs pasta quality. To maintain the yellow color that is mediated by flour carotenoids, pasta extruders […]

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Enhancing equine tendon repair: evaluating the synergistic effects of mesenchymal stromal cells and hyaluronic acid in a collagenase-induced injury model

This research project aims to enhance the treatment of common tendon injuries in horses, a prevalent issue causing economic losses in equine sports. Despite various treatments, there’s a crucial need for more effective solutions. The study focuses on comparing the impact of Mesenchymal Stromal Cells (MSCs) alone to a combination of MSCs and Hyaluronic Acid […]

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Assessing the Efficiency of Extracellular Vesicles for the Therapeutic Delivery of Modified mRNA

Extracellular vesicles (EVs) are tiny, membrane-based particles that cells release into various bodily fluids. They serve as messengers, facilitating communication between different cells in the body and, therefore, playing pivotal roles in modulating various biological processes. They achieve this by transporting a diversity of bioactive cargos, including RNA molecules. Over the past decade, our understanding […]

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In vivo and ex vivo anabolic potential of dietary amino acids with exercise

Resistance exercise training and the provision of dietary protein is known to bring about beneficial adaptations for muscle mass and strength. Substantial research has been conducted to identify the optimal protein supplements that permit the greatest anabolic response following an exercise stimulus. This research project will examine if a novel protein supplement can increase anabolism […]

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Portable Colorectal Screening Colorimetric Metabolite Biosensor

This project involves designing a portable biosensor that measures the concentration of multiple metabolites in a person’s urine. The device measures the colour of the urine after reacting with the developed reactions to get metabolite concentrations. These concentrations are input to an algorithm to get a diagnosis. The first test will screen for colorectal cancer. […]

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Role of Ribosomal Protein Ubiquitination in Chemotherapy- and Stress-induced RNA disruption in Tumour Cells

We have observed that chemotherapy agents can induce RNA degradation in tumour cells, a phenomenon called “RNA disruption”. Interestingly, we also found that high tumour RNA disruption after 2-3 cycles of chemotherapy predicts for complete tumour destruction after treatment and improved cancer patient survival. We and Rna Diagnostics, Inc. are using this knowledge to identify […]

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Wild Atlantic Salmon Watersheds

The rate and magnitude of environmental change present a threat to freshwater fish populations. In Atlantic Canada the impacts to the freshwater ecosystems will arise through elevated water temperatures, alterations in precipitation, variability in ice cover and frequency of natural and man-made disturbances. In addition, temporal and spatial changes to precipitation alter seasonal flow patterns […]

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Linking Soil, Vegetation Community, and Disturbance History to the Prevalence of Traditional Native Plants: An Indigenous-Driven Applied Research Initiative

There are disproportionate number of Federal Contaminated Sites found within Indigenous communities across Canada. As Indigenous peoples have unique ties to their lands, which serve as a means of sustainability and sovereignty, the impact of industrial processes on soil and vegetation within settlements is of utmost importance. This applied research project aims to address these […]

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Commercialization Potential of British Columbia Feral hops for the Canadian Hop Industry

The Canadian hop industry requires supportive resources from the scientific community to develop their own unique Canadian hop varieties with characteristics desirable to craft brewers. An alternative to the time- and labour-intensive method of selective breeding, new hop varieties may be obtained by identifying novel species in the wild. With its mild winters and long, […]

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The role of dietary alpha-linolenic acid in brain function

In multiple sclerosis (MS), the insulating ‘myelin sheath’ in the brain is damaged leading to neurological deficits. The repair of this myelin is important for the protection of nerve cells, but it is often incomplete. Dietary polyunsaturated fatty acids are thought to be beneficial, yet it is not well understood how these fats contribute to […]

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Synergistic effects of biological sex and sleep loss in an AD mouse model.

Women have a two-fold risk of developing Alzheimer’s Disease (AD) compared to men, though the cause of this risk remains largely unclear. Several studies have proposed female-specific risk factors (such as menopause) and modifiable risk factors (such as circadian disturbance), that could contribute to the exacerbation of AD pathology and symptoms through inflammatory mechanisms in […]

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Sexual health education needs of youth and educators in the Yukon

Research findings demonstrate that comprehensive sexual health education (CSHE) can reduce negative health outcomes and increase positive health outcomes. In order to be effective, CSHE must address the unique cultural, geographic, and social needs of youth. There are currently no studies that explore youth or educator sexual health education needs within the Yukon territory. SIECCAN […]

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