In Canada and worldwide, health systems are facing tremendous capacity pressures with aging populations putting increasing demands on health services. Caregivers play a vital role in supporting older adults at home. Caregivers often experience distress and burnout and need help navigating the health system. The overall goal of the project is to evaluate the feasibility […]

The proposed Research Plan is to evaluate the active targeting effect of glycan ligands for the delivery of conjugated lipid nanoparticles (LNPs) to human bone marrow CD34 + hematopoietic stem and pluripotent cells (HSPCs) and human peripheral blood mononuclear cells (PBMCs) such as T cells and B cells. A reporter mRNA will be formulated into […]

Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer. Its metastatic form (mRCC) remains incurable and resistant to chemotherapy and radiation. Current treatments targeting the tumor microenvironment offer limited benefit, highlighting the need for new strategies based on disease biology. ccRCC is difficult to target due to its cellular heterogeneity […]

Outdoor air pollution is a human carcinogen. This classification is based largely on a series of studies that has shown it increases respiratory cancers in adults. There is more limited evidence that that suggests it increases the risk of childhood cancer. To date, there have been few Canadian studies on this topic, and none that […]

Le climat de la planète se réchauffe rapidement, et les régions boréales du Canada sont parmi les plus touchées. Pour comprendre comment ces forêts réagiront au réchauffement actuel, il est essentiel de connaître comment le climat a évolué dans le passé. Ce projet cherche à reconstituer les variations de température des 13000 dernières années au […]

Chemical insecticides play an important role in global food production, ensuring reliable pest control and high crop yields. However, their intensive use also brings significant challenges—environmental contamination, risks to human health, and the rise of resistant pest populations. Addressing these issues is critical to maintaining both agricultural productivity and sustainability. This project seeks to discover […]

Bioactive compounds are naturally occurring food components that can promote human health, but they often lose their effectiveness because of problems such as low stability, low solubility, and poor absorption in the body. Encapsulation in emulsions is one promising way to protect these compounds and help them reach their target tissues, but the main limitation […]

SaskAgMatters (SAM) Mental Health Network Inc. is a support network created to offer a farm-culture friendly mental health support system for Saskatchewan (SK) Agricultural Producers (hereafter collectively called ‘farmers’). SAM offers six free counselling sessions with registered mental health professionals who have backgrounds in agriculture. SAM’s counsellors will be invited to semi-structured interviews focusing on […]

Plant cells naturally express enzymes that remove the reactive oxygen species (ROS) or prevent their production to a detrimental level under stress conditions. One such protective enzyme is the alternative oxidase enzyme (AOX) that is unique to plants among all other eukaryotes. There exist five AOX enzyme isoforms, AOX1a, AOX1b, AOX1c, AOX1d and AOX2, in […]

Au Canada, environ 8 millions de personnes souffrent ou souffriront de douleur chronique, un nombre en hausse avec le vieillissement de la population. L’ostéopathie, basée sur des techniques manuelles, vise à soulager ces douleurs et améliorer la fonction. Toutefois, l’ostéopathie n’est pas réglementée au Canada, et on en sait peu sur les ostéopathes et leurs […]

The interns will first conduct market research to determine the demands of the current life sciences industry, including pharmaceutical companies, gene therapy development companies, and companies that offer transgenic animal models. With this data, the interns will work together using a proprietary machine-learning algorithm from Re:Pair Genomics to design a catalog of 5-10 different compact, […]

The healthcare system relies heavily on blood and blood products for a large variety of life-saving treatments. However, blood products are perishable and have short shelf lives. Given the continuous demand for these products, this issue must be addressed. As blood is stored, the profile of cell surface sugars, known as glycans, has been shown […]