Anti-Inflammatory and Immunomodulatory role of Protein Hydrolysates: Involvement of microRNAs and Gut Microbiome

Studies related to the gut-lung axis have spiraled in the recent year, especially with current challenges related to COVID-19. The role of an optimal microbiome status for a well-functioning immune system is now emerging as a crucial factor to protect against immune-deregulation and infection in sites distant from the intestine. Therefore, this project aims to […]

Read More
Naturally produced cannabinoids for pain management and neuroprotection from concussion during participation in contact sports

This research will be a multi-centre project to investigate the effects of medical cannabis, i.e., cannabinoid formulations, on their neuroprotective and anti-inflammatory properties for concussion. We hypothesis that our CBD formulation can be used safely on a daily basis and will help to reduce the number and severity of concussions during contact sport competition. We […]

Read More
Comprehensive investigation of pesticides in honey, pollen, bees and soil collected from canola fields

In 2018, Health Canada proposed to phase out all agricultural uses of thiamethoxam and clothianidin neonicotinoids. However, after a comprehensive review, Health Canada decided (in March 2021) not to implement any changes for the use of neonicotinoids in canola production. While many stakeholders in the Canadian agriculture industry are pleased that Health Canada changed its […]

Read More
Modulation of proteinase receptor 2: a novel target for cancer immunotherapy

Treatments empowering patient’s own immune system (immunotherapy) have revolutionized cancer treatment this last decade, showing substantial clinical activity in different tumor types. However, 60% of cancer patients still fail to respond to immunotherapy and other standard of care. Our laboratory recently identified the proteinase receptor 2as a new target to overcome immunotherapy resistance. We propose […]

Read More
New insights into immunomodulatory effects of Spirulina in vitro, and on local and systemic adaptation to high-intensity exercise in horses

Exercise induced inflammation and subsequently free radical production are necessary for exercise recovery. However, excess inflammation may be detrimental to exercise performance and can contribute to degenerative inflammatory conditions such as arthritis in equine athletes. Algae, specifically Spirulina, has the potential to reduce the risk of degenerative disease without impeding post-exercise recovery and adaptation. Spirulina […]

Read More
Improving competitiveness and sustainability of pork production through increase in feed efficiency, improved carcass quality and higher animal welfare standards by innovative application of microbiome profiling, and computed tomography

Efficient animal production with a reduced environmental impact requires healthy animals, higher performance, increased feed conversion, and the use of available nutrients. The improvement of those traits could be accomplished by understanding how the gut microbiome plays a vital role in nutrient digestion and feed efficiency. Also, applying a reliable sorting tool allows identifying pigs […]

Read More
Development and Optimization of Freeze-dried Formulations of Ga-68 based cold kit and its performance evaluation by Radiolabeling and Animal Imaging

The student will be involved in the research and development of a novel multi-dose lyophilized vial kit for the preparation of Gallium 68Ga-DOTATOC injection used for the PET imaging of neuroendocrine tumors. This novel kit compared to the currently available ready to use injectable solution, has better shelf life and can be easily shipped to […]

Read More