Related projects
Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
Determine how cannabinoid metabolites and their relative abundances differ among marijuana strains. Post Doctoral Fellow Name: Teagen D Quilichini Cannabinoids are synthesized and accumulate in Cannabis plant hairs called glandular trichomes, which are particularly abundant on female flower buds. Cannabinoid content and composition vary dramatically among Cannabis strains, with two general groupings distinguished: marijuana strains, defined by high THC and low CBD levels, and hemp strains containing low THC and high CBD (or low total cannabinoid content). Marijuana breeding efforts have increased the cannabinoid potency and profiles of cannabis strains, and have produced marijuana strains with highly variable chemical phenotypes (chemotypes). While these breeding efforts have been successful in dramatically increasing THC levels, they commonly have reduced the content of other pharmaceutically valuable cannabinoids that compete for overlapping starter substrates (4). Many cannabinoids are known to have important pharmacological properties, and the relative abundance of the major cannabinoids (THC, CBD and CBC), minor cannabinoids and terpenoids can alter the therapeutic effects of marijuana strains. For instance, the presence of CBC augments some of the pharmacological effects of THC, while CBD has the ability to reduce THC side effects (5, 6).
Dr. Anne Lacey Samuels
Teagen Quilichini
Anandia Labs Inc.
Agriculture
Life sciences
University of British Columbia
Elevate
Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
Find the perfect opportunity to put your academic skills and knowledge into practice!
Find ProjectsThe strong support from governments across Canada, international partners, universities, colleges, companies, and community organizations has enabled Mitacs to focus on the core idea that talent and partnerships power innovation — and innovation creates a better future.