Developing a Field Deployable Assay System for Environmental Monitoring

There are currently over 9,000 potentially contaminated sites in Canada that require environmental assessment. The Field Deployable Assay (FDA) is a simple and cost-effective method for performing accurate environmental monitoring and site assessments. The FDAs are composed of a stationary main body and a variety of interchangeable cartridges. These cartridges act as miniature greenhouses, easily […]

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Presence of SSAT-1 as a marker for early diagnosis and monitoring of cancer

Cancer is one of the leading causes of death worldwide. In Canada, cancer accounts for 30% of all deaths, and half of all Canadians will develop cancer in their lifetime. Many cancers can be prevented or controlled through early detection, but the availability of such tests is scarce and a reliable general biomarker for different […]

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Proximate mechanisms behind carry-over effects mediated by key reproductive hormones in migratory seabirds

Long-lived animals, including seabirds, must balance investment in current reproduction with investment towards survival and future reproduction to maximize their lifetime fitness. Breeding is a critical stage in birds annual life cycle and requires high energy expenditure. Increased reproductive effort in the current year can therefore lead to costs that will have downstream consequences into […]

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Les meilleures pratiques à portée de main: Soutien au développement d’un programme de formation continue multi-composantes pour et par le Réseau Avant de Craquer

Les proches de personnes ayant un trouble de santé mentale peuvent obtenir du soutien dans les associations de leur communauté. À ce jour, le milieu communautaire n’a pas défini quelles sont les meilleures pratiques spécifiques à leur mandat qui est d’offrir du soutien psychosocial communautaire aux proches en santé mentale et ce, en fonction des […]

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Amélioration de l’ajustement des masques respiratoires grâce à la numérisation 3D, à l’analyse par éléments finis et à l’intelligence artificielle.

La pandémie de COVID-19 a souligné l’importance du port du masque pour prévenir la propagation du virus et le confort associé, notamment pour les travailleurs de la santé. En effet, l’efficacité d’un masque respiratoire dépend fortement de son ajustement. Avec les masques traditionnels, réaliser une étanchéité parfaite avec le visage s’avère difficile, voire impossible sans […]

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Modelling Acute Respiratory Distress Syndrome (ARDS) in Precision Cut Lung Slices (continuation)

As researchers strive to reduce the number of animals used in their research, many are turning to precision cut lung slices (PCLS), thin organ slices prepared from fully developed mouse lungs. They represent a “mini-model” that closely resembles the original organ in both anatomical structure and rich cellular environment. Despite the increasing interest, no commercial […]

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Immunotherapeutic targeting of CD133 in adult brain tumors and understanding tumor microenvironment in Glioblastoma

Glioblastoma (GBM) is an aggressive adult brain tumor, and in spite of standard of care (SOC) with radiation therapy and chemotherapy with temozolomide tumor re-growth (or recurrence) and patient relapse are inevitable. There is compelling evidence that suggests SOC can debulk the tumor but cells endowed with treatment-resistant properties (e.g. expressing the protein marker CD133) […]

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Spatial dynamics of sound beams in echolocating bats

This proposal uses advanced techniques in sound recording and analysis, statistics, and scientific computing to measure how echolocating bats adjust signal strength and the spatial geometry of their sonar beam to aid in auditory perception. A second but related project will compare vocalizations of young bats at different developmental stages and measure developmental changes in […]

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