The correlation and validation of functional markers and biomarkers for m/sTBIpopulations during simple and complex tasks – Year 1

This project aims to develop and validate markers for adaptive neurological performance therapies for persons with moderate-to severe traumatic brain injury (m/sTBI), with the purpose to further develop clinical paradigms for at-risk populations. In order to accomplish this, we have formed a collaboration between two Universities (Université Laval and McGill University) and two industrial partners […]

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Development of whole-heart model-based cardiac shape and motion analysis using parallel computing multi-core CPUs and GPUs technology

According to Statistics Canada, cardiovascular disease is the leading cause of death in Canada, accounting for 72,338 or 32% of all Canadian deaths in 2004. To further reduce the mortality and morbidity rate of heart disease, significant improvements in the extraction of the clinical heart parameters, such as the change in shape and motion patterns […]

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Biomarkers for detection of breast cancer and multiple myeloma using liquid biopsy

Blood tests are highly sought after to enable earlier cancer detection. We previously developed a blood test for breast cancer that is in prospective clinical study in Alberta, Manchester (UK), Oklahoma (USA) and South Korea. The proposed project will investigate some clinical samples collected through this work to support the primarily focus of identifying biomarkers […]

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Developing rAAV-mediated retinal gene therapy to improve vision for ZellwegerSpectrum Disorder – Year Two

Peroxisome Biogenesis Disorders of the Zellweger Spectrum (PBD-ZSD) are a group of inherited genetic disorders caused by mutations in any one of 13 PEX genes. Individuals with the common PEX1-G843D mutation consistently develop a retinopathy that progresses to blindness. To test whether we could slow visual loss in these patients, we performed a proof-of-concept trial […]

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Testing and Additional Development of a Novel Web Application

Aquaculture now accounts for approximately half of all fish and shellfish consumed worldwide. With increasing production costs and public concern over emitted wastes, there is much effort towards increasing the efficiency of operations, namely that of feed use. However, assessing the effects of the many factors contributing to productivity and efficiency, (eg. various feed types, […]

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Genomic tools development for international high sea salmon research

Pacific salmon spend most of their life in the open ocean, where we know little about the factors influencing their health and abundance. Last year, we participated in the first expedition to explore the winter habitat of salmon the Gulf of Alaska. We collect samples to inform ongoing research projects focusing on salmon health and […]

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Validation of the 12M inertial system against a marker based motion capture system

A new tendency, in the way of practicing and collecting data in the health related fields, has influenced a large development of non-invasive portable and wearable systems by companies specialized in biomechanical instrumentations. In human motion analysis, particularly in biomechanics, the use of inertial measurements units (IMUs) are frequently used in sports context such as […]

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