Related projects
Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
The emergence of viral pandemics, exemplified by the Coronavirus Disease (COVID-19), has exposed the urgent need for the development of viral infection therapeutics. In a short span of time, more than 1.5 million individuals have been infected and there have been nearly 90, 000 deaths worldwide. Our objective is to pharmacologically validate a new strategy for viral infection therapeutics by designing molecules that inhibit HDAC6, a protein implicated in viral entry. To address our objective, we will develop and optimize chemical compounds that target HDAC6 activity and then we will test the effects of these compounds on coronavirus entry and their anti-viral effect in cells. With our research we hope to validate a novel strategy for the development of anti-viral therapeutics to benefit the research community and advance public health objectives during a pandemic.
Matthieu Schapira
Mandeep Mann
Structural Genomics Consortium
Pharmacy / Pharmacology
Professional, scientific and technical services
University of Toronto
Accelerate
Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
Find the perfect opportunity to put your academic skills and knowledge into practice!
Find ProjectsThe strong support from governments across Canada, international partners, universities, colleges, companies, and community organizations has enabled Mitacs to focus on the core idea that talent and partnerships power innovation — and innovation creates a better future.