Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in […]

This study aims at determining whether an extruded soy bean meal may cause chickens to grow faster and contribute in reducing feed costs. A total of 480 chicks will be divided into 2 groups and fed one of two diets. In group 1, 240 chicks will be raised in 6 pens (n=40 each) and fed […]

Copper has long been proposed to have important biological properties. Designed to deliver the health benefits of copper, CuTEC yarn is a USPTO|EPO patent pending, bio-engineered copper-based yarn that can be produced as products such as clothing and mattress ticking. Although many believe in the positive properties of copper for well-being, many remain retiscent to […]

Running from the Greater Yellowstone Ecosystem to the northern Yukon, the Yellowstone to Yukon (Y2Y) region spans more than 1.3 million square kilometers across five American states, two Canadian provinces, two Canadian territories and the traditional territories of at least 31 Indigenous groups. It encompasses a wide diversity of ecosystems including alpine, forest, parkland, and […]

Fatty liver disease occurs in the setting of obesity and a high-fat diet, and involves a build-up of excess fat in the liver. Excess fat can cause injury to the liver, which can lead to scarring, and in some cases liver cirrhosis and cancer. As obesity rates increase, it is important to investigate possible ways […]

It is essential that calves are provided proper nutrition early on in life as they are the future of the milking herd. In addition to milk, many producers opt to provide solid feed, such as grain and forage, to young calves to foster gastrointestinal tract development. Solid feed can be provided as: 1) grain and […]

Au cours de l’inflammation, de nombreuses cellules peuvent s’activer. Dans ce contexte, les plaquettes sont reconnues pour générer des vésicules extracellulaires appelées microparticules, qui sont de petits fragments membranaires pouvant contenir des organelles comme la mitochondrie ou le protéasome. Nous avons récemment observé la présence de protéasome fonctionnel, essentiel pour la présentation antigénique, dans ces […]

The Safety Labs platform is an ‘always connected’ Internet of Things (IOT) cloud computing based system that focused on aging in place and well being for older adults through ongoing health knowledge. This project will focus on a trial with a population of older adults in the Ottawa region that will trial the system with […]

Dental caries affects the majority of the world’s population and causes tooth decay and loss. Bacteria in the mouth cause this disease. Sugar consumption plays a role in causing these bacteria to make acid that results in dental caries. Studies have shown that a type of sugar alcohol, called xylitol, can help prevent this disease. […]

Salmon are inarguably one of the most culturally, ecologically, and economically important fish in British Columbia, however, their stocks have been declining since the 1990’s. The Cohen Commission of Enquiry expert panel emphasized that juvenile mortality during the first months at sea was the most likely cause of fishery declines. This Mitacs project represents Phase […]

The net 5-year survival rate for patients suffering from liver cancer is less then 20 percent and the number of cases is rapidly increasing in Canada. Unfortunately, currently available oral chemotherapies can only extend median survival by 3 – 4 months making the development of new and effective drug treatments critical. The proposed study aims […]

The Centre for the Commercialization of Antibodies and Biologics (CCAB) is working with Empirica Therapeutics (Empirica), a Canadian start-up company focused on developing data-driven treatments for cancer, to address the unmet medical needs of glioblastoma (GBM), the most common adult malignant primary brain tumor. Current therapies are only partly effective, with frequent relapse and poor […]