Bacterial biofilms – Phytochemicals, efflux pumps and food safety applications

The partner organization is designing novel dispensing equipment for liquid products to be used by quick-service restaurants. A food safety concern related to the R&D of this equipment is the potential health hazards associated with the formation of bacterial biofilms within the dispensing system. Biofilms are complex bacterial communities that grow on surfaces contacting liquids. […]

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Ships and Whales in Gitga’at Territory: Assessing behavioral response

As whales recover from the past centuries of whaling and as global trade compels shipping traffic to increase, we expect negative whale-ship interactions such as fatal strikes and noise disturbance to become an increasingly serious issue. To develop cost-effective and broadly applicable methods of assessing the risks of ships to whale feeding grounds, I propose […]

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The use of crickets (Gryllus sigillatus) in poultry diets and their antimicrobial potential to defend against necrotic enteritis

The production of chicken requires a large amount of protein, and producers currently use antibiotics to help keep chickens healthy. However, there is a leading trend to reduce the amount of antibiotics used today, and with the growing population there is a need to find alternative protein sources. Insects, like crickets, could be a solution […]

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Antigen tracking of the DepoVaxTM-R9F cancer vaccine using MRI

Immunovaccine Inc. is developing cancer vaccines using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation that displays excellent tumor control and provides a long lasting and specific effect. The way by which this vaccine exerts its effect is unclear but the translational team at Immunovaccine is determined to discover its mechanism of action […]

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Glucocorticoids and Oxidative Stress in Bipolar Disorder

This project is on understanding the biological processes that underlie Bipolar Disorder (BD). BD is associated with dysfunctional oxygen metabolism and energy production, leading to the excess production of reactive oxygen molecules, which damage or alter the function of brain cells. Because BD is also associated with increased stress response systems, the current study aims […]

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Novel formulation for the treatment of interstitial cystitis

Interstitial cystitis is an inflammatory disease of the urinary bladder and is recognized as a serious medical condition associated with a profoundly negative impact on patients’ quality of life. Currently, there are no widely acknowledged causes of this disorder and no effective treatments available. Panag is a Halifax based drug company which focuses on development […]

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Factors influencing overwintering survival in the tick Ixodes scapularis, including the effect of infection with Borrelia spp.

The plan is to research the physiology and behaviour of Ixodes scapularis, and Dermacentor variabilis ticks with and without the presence of Borrelia burgdorferi bacterium, Rickettsia bacterium, Francisella bacterium, and Bartonella bacterium to answer the overarching question: Are tick-borne bacteria that are pathogenic to humans also harmful to the tick vectors in Nova Scotia? Cold […]

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Amélioration de la digestibilité des fourrages et diminution de la production de méthane chez les ruminants par l’optimisation de l’efficacité des protozoaires du rumen

Les camélidés partagent certaines caractéristiques anatomiques et physiologiques avec les ruminants. Bien que les camélidés aient une particularité microbienne telle que la présence d’un type de protozoaire spécifique à eux ‘’type B’’ et un genre spécifique nommé Butchlia permettant une meilleure digestibilité des fourrages par rapport aux protozoaires ‘’type A’’ chez les ruminants, on dispose […]

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Development of the Feldan Shuttle platform / Amélioration de l’activité cytotoxique des cellules Natural Killer (NK) en utilisant une stratégie d’invalidation de gène(s) cible(s) par technologie CRISPR

Feldan Therapeutic developed the Feldan Shuttle platform, a breakthrough peptide-based delivery method that allows the introduction of foreign proteins inside cells. The Feldan Shuttle overcomes delivery obstacles in therapeutic context by providing a safe and highly efficient approach that is associated with low regulatory burden. The Shuttle platform can transfer active nucleases and transcription factors […]

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Long-term response of boreal forest bird community to changes in habitat structure and configuration due to forestry and other land uses

There are both immediate and long-term effects of forestry on boreal birds. To minimize incidental take of birds and nests during harvest, foresters need accurate tools for predicting abundance of nesting birds in the peak breeding season, to time harvests year-round. Longer-term effects of harvest and other land uses on boreal birds are unknown, because […]

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