The main goal of this research project is to understand how the consumption of fructose can lead to the developement of hypertension. Hypertension is one of the most world spread health condition and a major risk factor for cardiovascular diseases, stroke and death. The high presence of fructose in the body, whether directly due to […]

In Canada, lung cancer is the leading cause of cancer-related deaths for both sexes. Non-small-cell lung cancer (NSCLC) constitutes ~85% of lung cancer cases. Mutations in the KRAS and EGFR genes are two most common oncogenic drivers for NSCLC and responsible for ~30% and ~15% of NSCLCs, respectively. Unlike the EGFR-mutant type, KRAS-mutant NSCLC is […]

Sinking is an important cellular response in diatoms that allows them to exit the upper mixed layer of the water column when conditions are unfavourable for growth. We know that diatoms have physiological control over sinking, but the underlying mechanism is not fully understood. The goal of my project is to identify the genes and […]

Saskatchewan is among the largest producer and exporter of pulses to various countries across the globe. However, pulses are not widely consumed in Canada. In Canada, the variety of pulse-based products is limited compared to those made from other legumes such as soybeans or from cereal grains. Consumers, including young children, will consume newly developed […]

In this research project a device is being developed and tested for its ability to permit the analysis of growing human tissues. Recently scientist have started to believe that cells need to be grown in 3D just like they are in our bodies. Similar to a cup, this device can be used to contain growing […]

Upcoming legalization of marijuana provides many opportunities for all Canadians. Licensed Producers (LPs) are the main providers of medicinal cannabis to patients and will be the main suppliers for recreational market. The significant disadvantage in the current environment is the limited number of strains available to LPs. Sundial Growers have acquired a collection of Cannabis […]

The diagnosis of Parkinson disease (PD), the second most common neurodegenerative disorder in the developed world, is based entirely on clinical criteria which are labour-intensive to apply and often inconclusive. Based on promising initial data from our laboratory, we will determine whether biochemical measurement of the enzyme, heme oxygenase-1 (HO-1) in saliva samples distinguishes PD […]

Diphtheria is still a disease causing significant morbidity and mortality in people worldwide that did not received vaccination or suffer from incomplete immunization. The disease is due to a powerful toxin produced by the pathogenic bacterium Corynebacterium diphtheria. A good vaccine already exists but its production is rather complex and involves several steps: cultivation of […]

Significant advances in technologies related to antibody discovery and development have allowed therapeutic antibodies to become the fastest growing class of biopharmaceuticals over the last 20 years. Northern Biologics is a biotechnology company that seeks to develop therapeutic antibodies for the treatment of cancer and fibrosis. Together with Dr. Jean-Philippe Julien at SickKids (University of […]

There are many ways for scientists to study lung diseases. One way that scientists try to understand lung disease is by growing and examining lung cells in the lab. While most cells are grown submerged in special liquid that provides the cells with nutrients, a more sophisticated model is to grow cells in an air […]

EMBERS Eastside Works (EW) is a new low barrier employment centre in the Downtown Eastside of Vancouver. EW helps people in the Downtown Eastside make connections to the world of work, earn income, and improve their livelihoods. The proposed research will work with EW to develop a database and information system that fits their needs, […]

The Arctic environment is changing rapidly, and this change may influence the health of organisms that live there, such as belugas. In periods of low sea ice extent, belugas in the Beaufort Sea showed altered expression genes involved in various aspects of health. Further, polychlorinated biphenyls, contaminants of concern, were also associated with altered gene […]