Imaging brain fuel metabolism in Alzheimer’s disease

Alzheimer’s disease (AD) is a major challenge for the individual affected, society at large and there only modest effective drug treatment. We believe that a central problem in AD is the deteriorating fuel supply to the brain (mostly the sugar, glucose) and this impairment appears long before the onset of memory and cognitive problems emerge. […]

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Using proteomic techniques to develop a systems approach for the discovery of biomarkers and drug targets towards cancer and other diseases

Gliomas are the most common type of CNS cancers, originating from glial cells. Glioblastoma multiforme (GBM) is the most common, complex and aggressive form of brain tumor found in human adults. GBM results from transformed glial cell progenitors. These glial cells have been found to arise from neuronal stem cells (NSCs), which reside in the […]

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UPnGO with ParticipACTION: Evaluating impact on the worksite environment and employee’s physical activity behavior

In order to improve the health and productivity of Canadians, ParticipACTION developed a rewards based, physical activity tracking intervention called UPnGO. The UPnGO pilot will aim to increase the amount of physical activity performed throughout the workday. Before and after the intervention, worksites will be assessed to determine what components of workplace environment and policy […]

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A pilot study of treating pressure ulcers with powdered Reconstituteable liquid Skin Substitute

Pressure ulcers are among the top five leading causes of re-hospitalization in patients with spinal cord injuries (SCI). Unfortunately, current conventional prevention and treatment methods have neither decreased the prevalence of these ulcers nor significantly improved their outcomes. To address this difficulty, here, we will test the efficacy of our new liquid skin substitute to […]

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Development of Cell-Based Functional Assays to Accelerate Commercialization and Therapeutic Application of Recombinant Antibodies

Antibodies are used for treatment of many diseases, including cancer. Within the human immune system, antibodies fight invading bacteria and viruses. We have devised a way to make high-quality antibodies in the laboratory and target them to specific disease-related proteins that have been identified by the scientific community and in our lab. Ensuring that these […]

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Can tree species mixing improve resilience and productivity of boreal forests?

The project aims at better understanding the role the stand composition may play in increasing resilience of the Quebec forests to future climate variability. We propose that by increasing the degree “mixing” of different species within forest stands, we can make forest more adapted to climatically unfavourable conditions, those frequency may increase in the future. […]

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Santé mentale globale: Accroître la capacité d’intégrer la santé mentale dans les soins primaires en Tunisie

En Tunisie, la majorité des personnes vivant avec des maladies mentales ne reçoivent pas de traitement. Le Ministère de la santé tunisien et le bureau de l’Organisation mondiale de la santé (OMS) à Tunis aimeraient offrir la formation mhGAP (développé par l’OMS) à des médecins généralistes afin d’accroître leurs compétences en santé mentale et créer […]

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Analyse du processus de passage à l’échelle d’initiatives innovantes développées dans le cadre des reformes du système de santé en Tunisie

Comme la plupart des pays en transition, la Tunisie est un pays qui est confronté à une restructuration constante de son système de santé pour faire face à différents défis. Dans la cadre de la nouvelle restructuration de son système, le gouvernement tunisien a décidé de mettre à l’échelle des projets les plus prometteurs et […]

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