Traitement adjuvant par hormone de croissance en fécondation in vitro : un essai randomisé et contrôlé.

Il a été suggéré que l’ajout d’un traitement par l’hormone de croissance (GH), pourrait augmenter les taux de grossesse en fécondation in vitro (FIV). Des études effectuées chez les mammifères, ont montré que la GH était importante pour le développement des follicules ovariens. Notre objectif est de déterminer si le taux de grossesse lors des […]

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Expression patterns of Wnt/?-catenin signaling pathway components in colon cancer

Extensive research focused on the identification of cellular signaling pathways involved in cancers. A tumor suppressor SOX7 has been implicated in several human cancers: it has been shown to suppress the Wnt/?-catenin signaling that is highly activated in breast cancer and ovarian cancer. This study sets out to determine the role of SOX 7 and […]

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Effects of GDF11 on proliferation and stemness of mesenchymal stem cells

The development of techniques that allow the culture and differentiation of stemcells has opened new research venues and the potential for novel therapies. It has been shown that transplantation of mesenchymal stem cells from bone marrow improved heart function after myocardial infarction. Also mesenchymal stem cells regulate cardiac electrophysiological functions of cardiomyocytes, and protect the […]

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Intestinal microbiota transplantation: a potential new therapy for colorectal cancer

Although it is known that the human gut is colonized by a wide variety of microbial populations, many effects of the complex interactions between the human host and microbial symbionts are still not completely understood. The dysbiosis or microbial imbalance of the gastrointestinal tract microbiota is considered to be one of the most important contributing […]

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Identification of Blood Biomarkers for Diagnosis of Peripheral Arterial Disease

Fasting blood samples from persons with Peripheral Arterial Disease (PAD) and healthy individuals were previously collected during a prior Mitacs project. A comparative analysis of the blood samples by metabolomics will be performed to identify potential biomarkers. The intern will assist with the necessary correlation analysis for selecting compounds capable of serving as blood biomarkers […]

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Microbiota characterization and modulation through the use of generated probiotic strains to combat colitis-associated colon cancer

A higher incidence of colon cancer is reported in populations consuming high amounts of red meat, as well as in patients with inflammatory bowel disease, where gut bacteria participate in the development of inflammation. We found that dietary supplementation with heme, an element found at high levels in blood, is detrimental to gut health and […]

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Characterizing the Fusarium species that affect major crops in Manitoba

Root rots caused by Fusarium species pose a significant challenge to soybean and pulse growers in Manitoba and Canada, and so does Fusarium head blight caused by F. graminearum. The potential for certain pathogen species to infect more than one crop, or crops in more than one plant family, represent a great challenge for producers […]

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Bobolink and eastern meadowlark occupancy in different agricultural land cover types

The bobolink (Dolichonyx oryzivorus) and eastern meadowlark (Sturnella magna) are listed as a species at risk in several Canadian provinces. Both songbird species are most abundant in Ontario and breed in hayfields, pastures, and other grassland-like environments. Ontario’s Endangered Species Act (ESA) seeks to protect these species by regulating activities that negatively affect their habitat. […]

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Deficit Irrigation and Crop Size Adjustment Strategies for Improving the Concentration of Aromatic Compounds in White Grapes in British Columbia Climates

In white wines, the wine aroma plays a major role in determining wine quality and economic value. In many grape varieties cultivated in BC, the aroma makeup is built in the vineyard where key aromatics accumulate in the grapes. Irrigation and crop size adjustments are two main strategies that growers have adopted to manage fruit […]

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