Periodontitis is a polymicrobial infectious and inflammatory disease that can lead to destruction of supporting structures of teeth. Although pathogenesis of periodontitis includes genetic and environmental factors, oral microbial biofilm elicits an inflammatory host reaction. Improvement in patients with periodontitis relies mainly on elimination or at least control of periodontal pathogens. The aim of this […]

Ce projet vise à mesurer, d’une part, la faisabilité et l’acceptabilité d’un programme d’activité physique faisant appel à une gérontechnologie auprès des aînés vivant en résidence pour personnes âgées et, d’autre part, les bénéfices d’une telle d’intervention auprès de cette population. Nous faisons appel à une technologie adaptée appelée Jintronix qui offre une variété d’activités […]

The hypothalamic paraventricular nucleus (PVN) is an area of the brain that plays an important role in processing information regarding body homeostasis. Neurons within this area can directly detect circulating signals regarding homeostasis, such as molecules and peptides. Arginine-vasopressin (AVP) and oxytocin (OXT) are two peptides found within the PVN that are thought to be […]

Ce projet a pour but de mieux comprendre les impacts de l’installation de membranes de jute pour le contrôle des plantes aquatiques envahissantes sur la biodiversité des lacs. En collaboration avec un organisme de bassins versants, nous recouvrirons de jutes des portions d’un lac colonisé par le myriophylle à épi. Cette espèce exotique envahit de […]

With the advancement of magnetic resonance imaging (MRI) techniques, an exciting time has emerged for research in the field of cerebral anatomy and physiology. The basis of this proposal is to employ a one of a kind imaging technique to drive forward our basic understanding of regional blood flow regulation in the human brain. The […]

Gene expression in blood is highly affected by the type and proportion blood cells. Therefore, cell composition needs to be taken into account when looking for signatures specific to a condition. The issue is that cell composition needs to be assessed on fresh blood, i.e. at time of blood collection. If this has not been […]

Circadian rhythm disorder is when the body’s biological clock is altered, leading to patients sleeping 3-4 naps of 1-4 hours throughout the 24-hour period instead of a continuous 8-hr sleep session. This form of insomnia greatly decreases the quality of life in the patient. We want to know whether if the altered circadian rhythm reduces […]

Des études récentes semblent indiquer que les coupes partielles ne seraient pas aussi bénéfiques qu’on le croyait en termes de conservation de la biodiversité et du fonctionnement des écosystèmes forestiers par rapport aux coupes totale. Les coupes partielles sont toutefois utilisées de plus en plus fréquemment pour répondre à des objectifs de protection de la […]

A recently developed technology called CRISPR/Cas9 allows scientists to quickly and precisely edit DNA in living cells and is about to revolutionize molecular biology and genetics. The success of CRISPR/Cas9 is based on its ease of use, effectiveness and cost efficiency. Our aim is to explore a variant of this technology, CRISPR/Cpf1, for its application […]

New species may arise when related animal populations diverge in their plumage and song mating signals and no longer respond to the signals of other populations. In many tropical birds, species limits are unclear because of a lack of studies on plumage, song, morphological, and genetic variation among closely-related populations. Even fewer studies investigate whether […]

The return on investment for medical imaging, interventional radiology, is not well understood, with limited existing research on the value realised from the funds spent. It is expected that the Hot Stroke Intervention by interventional radiologists will not only add direct value to the health care system but will have far reaching and significant impact […]

The complexity of movement and behaviour in Pacific herring (Clupea pallasii) stocks targeted by commercial and indigenous fisheries in BC is poorly understood and often discounted in fisheries management policies, possibly contributing to recent stock declines. We propose to inform spatial management strategies for herring on the central coast of BC with (I) local knowledge […]