Fabricate Hydrogel Scaffold Encapsulating Living Cells for Myocardial Infarction Repair

To solve the issue of complementing cell loss or stimulating angiogenesis for repairing MI, scaffolds encapsulating living cells, which aim at inducing cell proliferation and differentiation, are designed and then synthesized based on biocompatible and biodegradable materials. The experiments are performed by applying them to 3D cultured MDSCs for cell proliferation and differentiation study via […]

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Évaluation de la faisabilité d’utiliser et d’implanter le programme Jintronix à domicile dans le but de prévenir le déclin fonctionnel chez des aînés encore autonomes qui consultent les urgences

Chaque année, environ 10% des canadiens autonomes (65 ans et +) subissent des blessures mineures (fractures, entorses) conduisant à un déclin fonctionnel (pertes de mobilité et d’autonomie). 65% d’entre eux auront recours aux urgences après leurs blessures et 18% auront un déclin fonctionnel 3 à 6 mois après leurs consultations aux urgences et seront dans […]

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Real-time fatigue detection by remote eye tracking

Fatigue is a significant risk factor for operating moving vehicles in work settings that involve long duty hours or shift work rotations. A critical objective in fatigue management is to develop technology to establish fitness for duty, monitor fatigue in real time and predict performance failure. Eye movements (eyelid closure, blink rate and duration) are […]

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Création d’un panel pharmacogénomique et élaboration d’une base de données translationnelle

À chaque année, des milliers d’individus souffrent ou décèdent suite à l’administration d’un médicament qui n’était pas approprié pour eux. Grâce aux récentes découvertes en génétique, il est maintenant possible de mieux prédire comment un individu va répondre à divers médicaments en analysant ses variations génétiques. Hors, un service de séquençage génétique n’est toujours pas […]

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Metagenomic study of dechlorinating microbial communities invitro and in situ, part 2

The project is focused on study of commercial microbial cultures for biological remediation of soils and ground waters contaminated by chlorinated organic compounds. The successful elaboration and improvement of the products requires analysis on molecular-genetic level and detailed understating of organization of the microbial communities. The work benefits to industry partner by providing comprehensive information […]

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Intrafibrillar vs surface mineralization in bovine flexor tendon-derived collagen fibrils – an in vitro model of calcific tendinopathy of the human Achilles.

Calcific tendinopathy (CT) is a staged, reactive process where pre-calcific changes are followed by a calcific phase (formative, resting, resorptive) and by post-calcific remodelling in which hydroxyapatite-like deposits form and quite often resorb spontaneously. CT is most prevalent in the neck, foot and hip and within the foot. The Achilles is a well-documented site of […]

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Health risks of agricultural intensification in Vietnam

During the last couple decades, agricultural practices have increased in intensity to meet the growing needs of economic growth and population growth in Vietnam. Increased livestock production, management of human and animal waste, hormone and antibiotic residues from humans and livestock present human and environmental health concerns. The risks of agricultural intensification to human health […]

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Assessing Social Cognition in Autistic Youths and Adults

The goal of the project is to develop a series of standardized, performance-based computerized assessment tools for use in the examination of social cognition deficits in ASD. Drawing on the available experimental literature a number of potential assessment tasks will be identified, reviewed and configured for computer-based administration to children / youth with ASD. Programming […]

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UNDERSTANDING THE MECHANISMS OF VIBRATION PERCEPTION BY PLANTS

Plants are not passive bystanders, they sense their surroundings and react to threats through chemical and vibrational cues. A key example of this is when a plant detects volatile organic compounds (VOCs) released by neighboring plants that have been damaged by herbivores. Green leaf volatiles (GLVs), a subset of VOCs released in the atmosphere, are […]

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Enzymatic hydrolysis of wheat straw derived xylo-oligomers stream into monomeric sugars

The proposed research project is around re conducting feasibility studies on the purification and conditioning of industrial hemicellulosic C5 sugars from a number of potentially commercial wheat straw liquor fractions. The research will propose experiments where data for the ultimate evaluation of enzymatic hydrolysis vs. a selected comparative list of acid hydrolysis can be included. […]

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Social aspects of biodiversity conflicts: the case of human-jaguar coexistence in Calakmul, Mexico

Biodiversity conflicts considering human-wildlife interactions have usually been addressed in regard to the impacts of animals on human beings or properties and, conversely, of humans on animals, with the ultimate goal of reducing those impacts. However, this has rarely lead to long term conflict resolution, which suggests that conflict management should reside further than in […]

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Improving efficiency and complexity of reporting for epidemiological insights and disease trends

Globally, there have been challenges in pulling together data, analyses, epidemiological insights, and unusual infection disease trends into comprehensive and regular reporting, that support pharmaceutical and life sciences organizations with timely intelligence for decision making. BlueDot has the knowledge and expertise to bring together these insights in a highly visual, easily understandable regular reporting format, […]

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