The ability of couples to conceive is highly dependent on hormonal levels. With age, conception becomes more challenging and there is a direct need for women to control their fertility by monitoring their hormone levels, mostly Estradiol. The purpose of this project is to develop an at-home testing kit for estradiol monitoring. By developing a […]

This project is aimed at understanding evaluating and reviewing gene therapy methodologies used in products in development, assessing the risk and safety and regulatory investigations in different regions of the world. There is limited guidance and regulatory expertise in this area and current drug candidates are being dealt with on a case-by-case basis by the […]

In the context of science teacher shortages in both countries, this exchange proposes to use already-collected data to compare and contrast how young people with a specialism in science in both the UK and Canada view the prospect of becoming a science teacher. This comparison will develop understandings of who does, and importantly who does […]

The use of cocaine and heroin among young Europeans and Americans has been steadily increasing over the past decade (UN World Drug Report, 2018) and as such it has never been more important to understand the mechanisms whereby some individuals switch from recreational controlled drug use to compulsive drug seeking, the hallmark of drug addiction. […]

Currently, the service provided by GRAD4 allows buyers to upload their designs for quotes from the suppliers. However, there is no initial manufacturability check for buyers to evaluate their parts before submitting their quotes. Buyers may get feedback from the suppliers, which indicates that their parts are not able to be manufacturable after a several-days […]

Underground metro infrastructures are subjected to different types of dynamic loads that would hinder their ability to function properly. This proposed research aims to assess the risks of city-scale underground tunnel networks under both periodic human-induced vibrations (i.e., blasting and drilling vibrations) and short-term extreme earthquake hazards. We will develop a GIS model for the […]

Adults exposed to extended periods of static seated computer work, especially females, have elevated risks of developping musculoskeletal symptoms. However, static standing work is also associated to issues with the musculoskeletal and vascular systems. To address this, alternating between seated and standing postures has been proposed in the form of sit-stand desks; however, their sex-specific […]

HyperMabs is a biopharmaceutical company that designs and develops innovative therapeutics targeting lung diseases. HyperMabs is currently evaluating a drug candidate developed using in-silico methods to target lung disease. For this project, we aim to study the biodistribution of HyperMabs therapeutic, currently in its pre-clinical stage designed to treat several lung diseases. To achieve this, […]

Hydro power generates a large proportion of Canada’s electricity, and is by far the largest source of renewable energy. Modern hydraulic turbines are highly optimized with respect to size (cost), power output and efficiency. One of the main factors limiting further efficiency increase is cavitation. Cavitation occurs where the local static pressure drops below vapor […]

This project concerns the efficient simulation of constrained-multi body systems with applications in training simulations. For instance, a crane on a construction site can be modeled and simulated as a collection of rigid bodies connected by rotational joints. Simulation of contact and friction is similar but a challenge because the force is bounded (i.e., forces […]

Once produced, electricity is difficult to store in large quantities. Hence, accurate electric load forecasting is of critical importance to balance production and consumption for modern power grids integrating more and more intermittent renewable energy and variable loads such as electric vehicles. Short-term electric load forecasting for local areas is also of interest to efficiently […]

Two types of color changes occur in potato, raw potato darkening and after cooking darkening. We are investigating the factors behind each type of darkening in three potato cultivars (Chieftain, Goldrush, and Yukon Gold). Effect of digging method (hand/mechanical) and storage time (after 3, 5, and 7 mo) were studied to find if the digging […]