The Development of Multifunctional p53 Reactivators for Cancer Therapy

The p53 protein plays a major role in cancer prevention, and over 50% of cancer diagnoses can be attributed to mutated p53. The main function of p53 is to prevent uncontrolled growth of damaged cells and inhibit tumour formation. Mutant p53 has provided a unique opportunity to design multifunctional molecules that act on different aspects […]

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Electrochemical Interfaces for Green Hydrogen Production

Water electrolysis has attracted attention as a sustainable and clean means for the production of hydrogen. Research focus is shifting from proton exchange membrane (PEM) water electrolysis towards anion exchange membrane (AEM) water electrolysis. However, there is a gap between studies of electrode materials in aqueous electrolytes and real devices utilizing ion conducting membranes. The […]

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Developing CLEWs Modelling Tools to Support Sustainable Development (2)

The Climate, Land, Energy and Water systems (CLEWs) model allows for representation of the Nexus interactions between different sectors. Applied in Sustainable Development contexts, the CLEWs model enhances policy coherence and supports effective decision making. This project will enhance and build on the existing CLEWs tools to make them more robust, enhance the ability of […]

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Ayazazi

AYAZAZI (meaning ‘Knowing Themselves’ in Zulu) was a CIHR funded youth-centred, multi-site, interdisciplinary, prospective cohort study focused on HIV prevention among 425 adolescents and young adults (aged 16-24 years) residing in Soweto and Durban, who reported HIV-negative or unknown status at enrolment. AYAZAZI is guided by a youth engagement framework, which prioritizes youth-friendly spaces and […]

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Expanded Assessment of Climate Change-induced Geohazards for Ice-clad Canadian Volcanoes and Mountains

In Canada’s mountains, climate change is leading to the retreat of glaciers, permafrost thawing and accelerated snowmelt. These factors contribute to a significant increase in slope stability hazards and the risk of landslides, placing numerous communities and critical infrastructure at risk. Volcanoes are particularly vulnerable as they are commonly hydrothermally altered and weakened, thereby compounding […]

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Development of novel therapeutics for multidrug-resistant bacterial pathogens by targeting indel-containing essential proteins

Multidrug-resistant (MDR) bacterial pathogens are ubiquitous in hospitals and community settings. New antibiotics against unexploited targets are urgently needed to better control such infections. The proposed research aims to identify novel, drug targets and therapeutics for antibiotic-resistant nosocomial pathogens, capitalizing on a proprietary indel-targeting approach that takes advantage of structural differences between homologous essential human […]

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GaN Modelling for the EV Application

The use of new technologies, such as Gallium Nitride electronic switches, allows very efficient and compact power converters to be manufactured at reasonable cost. This is particularly interesting in applications such as electric vehicles. This project focuses on developing software simulation models and techniques for deploying these latest high voltage switches, in particular focussing on […]

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InterGenNS [Intergenerational North Shore] Project: An Inclusive Vision for Facilitating and Sustaining Intergenerational Community Building Strategies

In response to the vast amount of interest in the North Shore pertaining to intergenerational initiatives, this project seeks to bridge community agencies academic research to provide tangible tools and resources to broaden the awareness of activities connecting different generations in the North Shore to actively contribute to reducing social isolation and loneliness, while enhancing […]

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Using Resource Public Key Infrastructure for Secure Border Gateway Protocol

BCNET’s mandate is to provide shared technology services such as cloud computing, VoIP, disaster recovery solutions, and telepresence to its members using an advanced network connected to the backbone of the Internet. Today, the core members of BCNET are UBC, UVic, SFU, BCIT, TRU, and UNBC. Any attack may interfere in the operation and the […]

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Reinforcement Learning Algorithm for Traffic Signal Control to Reduce GHG Emissions

Persistent traffic congestions which are varying in volume and duration in the cities are not just the source of frustration for drivers, but also one of the biggest sources of greenhouse gas emissions in the world. Those types of congestions cannot be adequately resolved by the traditional traffic signal controllers. Breeze Labs Inc. in cooperation […]

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Autonomous Energy System; Scalable, Flexible, Light and Low Cost – part 2

Nowadays the most rewarding aspect of engineering is to create solutions to the needs of society in a natural and resource efficient manner, therefore we must come up with more innovative and resource efficient solutions. One such solution can be a novel scalable autonomous energy system, which integrates Organic (polymer) based photovoltaics (OPVs), high density […]

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