Many therapeutic targets are proteins embedded in the membrane that surrounds the cell. Traditionally, such targets present major challenges, because they required the use of detergents to extract them from the membrane and to purify them. Such detergents can cause artefacts, hampering the development of novel therapeutics. Here we will test new methods that get […]

Lamps and lighting products are the most commonly used electrical product around the globe. With the improvement in lamp technologies, from incandescent bulb to compact fluorescent lamp to LED bulbs, the products have grown complex and hence they require an improved recycling process. In general, lamps consist of various valuable metals such as iron, copper, […]

The Centre for Operations Excellence Industry Projects consists of six sub-projects sponsored by five different industry partners. Each sub-project represents an important challenge for its sponsor. These sub-projects include assessing the effects of traffic interventions at airports (Boeing 1), simulating demand for flight simulator training (Boeing 2), predicting return to work outcomes using unstructured data […]

With the maturity of renewable energy technology in recent years, micro-network has become an ideal power supply solution to the remote villages and islands. Recently, researchers have tried to reduce the cost of the system based on ideal assumptions. However, the factors that actually affect the system life cycle cost are varied. Including the control […]

The major focus of this proposal is to perform preclinical studies to support clinical development of a novel inhibitor for treatment of different caners such as breast, lung, colorectal and kidney. We have recently developed a novel therapeutic protein that selectively inhibits multiple pathways for treatment of advanced prostate cancer. A goal of this project […]

High Dynamic Range (HDR) content and displays are available on the market but the vast majority of the users displays are Standard Dynamic Range (SDR), not able to reproduce the enriched, higher quality and with more details HDR content. Thus, operators to compress the HDR content and make it ready to be able to be […]

With the onset of climate change, sea level rise is a major global concern including distinct local issues. This project looks at the extremely venerable coastal city/port city of Vancouver. Recent reports call for major infrastructure improvements primarily focused on engineering and not on spatial and design approaches to this challenge. Currently there is no […]

The physicochemical character of the hydrological regime that formed Carlin-type Au-deposits (CTGDs) are poorly understood and represents a critical knowledge gap relating to their genesis. We are undertaking an integrated geological and geochemical study of the Nadaleen trend of CTGDs in the Yukon to better define the hydrological regime that controlled their formation. The proposed […]

Traditional oil sands production techniques include mining and transporting the sands and in situ production using steam injection, Steam Assisted Gravity Drainage (SAGD). This proposed method will replace or enhance SAGD by using primarily traditional vertical well bores and an induction heating method which will potentially allow the heating effect to expand in diameter as […]

OMiCS represents a broad research initiative exploring the relationship between physical literacy (PL) in children and markers of biological health. The research seeks to expand on the literature surrounding the components of PL: physical competence, confidence, and motivation for being active, and determine whether any of these components can shift objective biomarkers of health (the […]

The alignment of the dissertation and the CE in terms of preparing students as researchers in today’s environment or for innovative work outside the academy is in question. The purposes and structures of these basic PhD components have not changed significantly since the origin of the modern PhD, which was developed primarily as a vocational […]

Onsite Domestic Wastewater Treatment and Reuse is emerging as a potential solution to the water shortages, eroding distribution infrastructure, and energy intensive treatment processes that are a fixture of the modern city. However, existing onsite treatment technologies fail to compactly treat water to a high enough quality for urban reuse without increasing per capita treatment […]