Mevalonate Cascade Inhibition Sensitizes human Glioblastoma Cells to Temozolomide via Modulation of Autophagy

Glioblastoma multiforme (GBM), also known as glioblastoma and grade IV astrocytoma, is the most common and most aggressive cancer that begins within the brain. There is no clear way to prevent the disease. Typically treatment involves surgery after which chemotherapy and radiation therapy is used. The medication Temozolomide (TMZ) is frequently used as part of […]

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Computer Vision and Deep Learning for Moderating Visual Content

Two Hat Security is a company that develops next generation moderation tools for social networking apps. Since visual content (e.g. images, videos) is one of the most important types of data shared by social networking apps, an important problem for the company is to identify images/videos that are offensive or inappropriate. For example, certain images/videos […]

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The Impact of Renovations in Long Term Care Living Spaces on Residents with Dementia, their Families and the Staff that Care for Them

Riverview Health Centre (RHC) plans to renovate their special care units and grounds, which accommodate 60 residents with intermediate and advanced stages of dementia. The main purpose of this study is to examine the effects of the renovations on residents, family and staff using a multi-methods research approach and a multi-disciplinary team of researchers (i.e., […]

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Feasibility Study of a TV-Based Video Chat Technology for Elderly with Dementia

According to the Canadian Institute for Health Information, many of Canada’s increasing aging population experience physical and cognitive impairments that necessitate moving to a care facility, with 44% of these residents having or indicating symptoms of depression. Social isolation is a contributor; 22-42% of these residents reported feeling severe loneliness. Video chat sessions have been […]

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The Semaphorins, a role Inflammatory Bowel Diseases

Inflammatory bowel disease (IBD) includes both Crohn’s disease (CD), and ulcerative colitis (UC). Approximately 230,000 Canadians are affected by these diseases and they have important repercussions on quality of life and on both personal and societal direct and indirect costs. The cause(s) are poorly understood, and treatment is largely symptom-based and not curative. Commonly used […]

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CHALLENGES AND OPPORTUNITIES FOR THE MANITOBA MEDIA PRODUCTION SECTOR IN THE DIGITAL MULTIPOLAR GLOBAL LANDSCAPE

This research aims to contribute to improving business strategies to leverage the Manitoba Media Production Sector (MPS) position at the global level. The project structures itself on a synergetic partnership between On Screen Manitoba, a NFP industry association and the Geopolitical Economy Research Group from the University of Manitoba, directed by Radhika Desai and former […]

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Probabilistic Evaluation of Distribution Networks Containing Distributed Energy Sources, Energy Storage and Electric Vehicles

After introducing deregulated power markets and small scale distributed generation (DG) in power distribution systems, the probabilistic evaluation gained much attention to quantify the uncertainties due to parameters such as wind speed, solar irradiation, power market price etc. Meanwhile, due to increasing penetration of electric vehicles (EVs), the load demand due to EV charging has […]

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Characterization of chemosensory proteins in exosomes

Cells in our body secrete round structures lined by cell membrane under normal as well as stressful conditions. These “structures” or “micro vesicles” are termed as exosomes. They contain information from parent cells that can be transferred to other cells, thereby acting as cell-to-cell communication units. In this study I aim to identify the presence […]

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Micro and Nano-structural Elements of Flax and Hemp Fibres Sourced inManitoba.

Improved application of hemp and flax fibres in advanced materials will promote Manitoban agriculture and associated industrial production in the emerging bioeconomy. The proposed research will provide, via high resolution chemical mapping, the fundamental science platform required for the rational design of advanced, sustainable biocomposite materials, combining appropriate fibre-matrix complexes de novo. It will augment […]

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Investigations into the stability of large power systems with embedded power electronic subsystems using frequency impedance scanning

In this study, an advanced frequency scanning method is used to extract the frequency dependent network equivalent (FDNE) impedance characteristic of a power electronic subsystem such as an HVDC transmission system or FACTS device including its controls. This is achieved by simulating it in the time domain on an EMT program, and exposing it to […]

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