NorthMiRs is developing nanotechnology-enabled gene therapies for the treatment of sepsis. We have determined microRNAs that are dysregulated in septic patients and packaged them into a stable, synthetic, and scalable lipid nanoparticle delivery vehicle. Our lead therapeutic, NM-001, a miRNA replacement therapy for sepsis-associated cardiomyopathy has been shown to be anti-inflammatory, anti-microbial and protects organs […]

EPAID Technology: EPilepsy AI-Driven Technology aims to automate electrophysiological signal processing practice to assist clinicians in the treatment of epilepsy. We will partner with Springboard, who provides strategically positioned resources to Atlantic Canadian universities and colleges alike, helping them transfer both knowledge and technology into the private sector.

Myelofibrosis is a chronic and life-threatening blood disease. There is a need for accurate risk stratification approaches to guide personalized medicine decisions for these patients. To address this need, we developed a non-invasive blood-based test that is cost-effective, scalable and accurate. Through the Lab2Market program we will explore the market and develop the business case […]

The range of contemporary engineering careers extend far beyond those closely tied to the traditional disciplines taught in engineering schools. Using Canadian Census 2021 data, this study will examine the occupational outcomes of engineering graduates residing in Ontario, with specific attention to the differences between industry sectors of employment and along lines of race, gender, […]

“RemoteCare” is a novel initiative that empowers individuals to conduct part of their medical assessments independently via a user-friendly remote digital solution. By enabling self-assessments, it reduces physician workload, minimizes wait times, and ensures quicker access to medical assistance, especially in underserved areas. However, its progress hinges on gaining the trust of traditional healthcare providers, […]

In Canada, heart failure (HF) has a 30-day re-admission rate of 17.6%. While patient care at home via follow-ups and self-management may reduce this rate, factors including physical fatigue and cognitive frailty delay follow-up visits and impair the patient’s ability to self-manage. An implantable solution such as CardioMEMS is available to monitor HF, however, its […]

In this study, patients with idiopathic scoliosis followed at SickKids will undergo topographic analysis using the Momentum Health scanning application in addition to standard of care clinical evaluation and x-rays. The study period is 1 routine clinic visit followed by 3 months after. Patients will self-scan 1x/month at home for the following 3 months. The […]

The proposed project aims to demonstrate the application of an analytical framework, developed by the team at the University of Toronto, to plan on-demand transit services in Mississauga. The analytical framework will be enhanced with an in-depth investigation of existing simulation tools with respect to their adequacy for modelling various ODT scenarios and operational designs. […]

Metal additive manufacturing (AM), or metal 3D printing, enables “unique structures printed for unique functions” and “the right materials printed in the right place”. Therefore, it is the preferred fabrication method for creating functionally graded materials (FGMs), whose material properties varies over its volume to meet industrial needs. In this project, I leverage external magnetic […]

The project investigates the distinction between two main forms of human memory, namely episodic (the experiential contextualized memory for personal past episodes) and semantic (the abstract de-contextualised memory for facts) memory. In line with recent proposals in philosophy, it calls this widely accepted distinction into question and explores a one-system conception of memory. The original […]

The proposed research project aims to understand to what extent Canadian neighbourhoods vary based on the accessibility of transportation and identify which socially disadvantaged groups of people are most impacted by limited access to transport. The interns will analyze a large dataset released by “Infrastructure Canada and Statistics Canada” which measures how easy it is […]

Cerebral Cavernous Malformations (CCM) are brain vascular malformations which occur in one person out of 200. Their consequences are devastating as they provoke epilepsy, stroke and many neurological disorders. CCM develop only in low blood flow venules and not in arteries in which the high flow has a protective effect. Yet, why CCM lesions form […]