Despite the power of gene therapy, its successful application to medicine has been diminished due to: (i) high toxicities and potentially fatal adverse effects; (ii) poor transgene expression in target cells; and (iii) extensive vector degradation. While viral vectors greatly improve efficiency, they sometimes lead to cancers due to chromosomal integration and may suffer from […]

Digital pathology uses modern scanners to capture high-resolution images from biopsy samples. Computer algorithms, especially artificial intelligence, can help in automatic searching for similar cases in the archive of hospitals and laboratories. Displaying similar images form the past patients, that have already been diagnosed and treated, can provide useful information to the pathologist to solidify […]

In many developing countries, it is very difficult to survey vulnerable groups in a way that provides reliable research findings. These surveys also only give limited insights into the experiences of these populations. This project will develop a software program that can be used to model the probability of events occurring given the estimated probability […]

The Building Block Approach (BBA) is one of the liability measurement approaches proposed in the new insurance contract standards – International Financial Reporting Standards (IFRS) 17. Of the three components under BBA, determining the risk margin is the most essential. This project will develop a model that would determine the risk margins and claim provisions, […]

The emerging emissions trading market provides the province of Alberta an opportunity to diversify its economy and drive climate change mitigation innovation. By improving the carbon credit generating efficiency, more economic opportunities and carbon sequestration industrial applications become feasible. The City of Calgary Dewatered Biosolids Land Application – Willow Biomass and Marginal Land Reclamation Demonstration […]

Physiotherapy is a type of rehabilitation that aims to restore a patient’s quality of life after an injury, surgery, or stroke by improving their mobility. Through prescribed exercises and specialized equipment, physiotherapy helps the patient to regain their muscle strength, range of motion, and natural movement. Unfortunately, only rudimentary tools are available to the therapists […]

In this project, charging and driving data of 1000 electric vehicles (EVs) across Canada will be monitored and analyzed to figure out the impact of EVs on the electrical power grid, and their potential capability to reduce CO2 emissions. For this purpose, the degree to which a particular electricity grid profile, the vehicle type and […]

A social-ecological systems perspective analyzes the connections between human impacts and ecological components. Regime shifts are rapid changes in an ecosystem’s structure and function. They are often difficult to anticipate and either extremely costly or impossible to reverse. A gendered lens is crucial in analyzing these shifts as gender roles have been constructed by society, […]

The majority of hydrocarbon in Canada is produced from the unconventional reservoirs characterized by ultra-low matrix permeability. Hydraulic fracturing is a common stimulation technique used in oil and gas industry to release hydrocarbon trapped in the rock making the hydrocarbon recovery economical. The ability to model this process may lead to the efficient hydraulic fracturing […]

The crew pairing problem begins with a time table of flights and a fleet of available aircraft. The time table is created from considerations such as available slots at airports, available aircraft, aircraft specifications, airport limitations, projected load factors and passenger demand. After the timetable has been set and aircraft have been scheduled to that […]

The goal of this project is to design computationally-efficient solvers that can be used for autonomous vehicle control developments. Because autonomous cars have complex mathematical models, it is usually hard to perform their necessary control computations on-line and when the vehicle is running. Therefore, it is required to come up with much faster solvers for […]

The research will look at the use of community-managed marine protected areas (MPAs) to deal with abrupt and long-term environmental and social changes taking place in the Ria Lagartos Biosphere Reserve, Merida, Mexico MPAs have long been used to protect marine species and ecosystems, but their social considerations have yet to be fully studied Information […]