Innovations thérapeutiques ciblant le récepteur à l’apéline dans les cancers localement agressifs

La prise en charge thérapeutique des cancers localement agressifs, dont font partie les cancers de l’ovaire (OvCa) et les glioblastomes (GBM), est aujourd’hui encore un enjeu majeur, avec une survie à 5 ans de 30% et 4% respectivement. La communauté scientifique se penche sur l’identification de nouvelles stratégies thérapeutiques afin de pouvoir proposer des traitements […]

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Functional analysis of subgroup IV CDPKs in soybean

Soybean stands as one of the major field crops globally. However, its production encounters annual yield losses, partially attributed to pathogenic threats. To enhance the immunity of crops such as soybean, it is crucial to comprehend the molecular mechanisms of immune signaling. Building on our prior research, we propose that specific CDPKs may represent promising […]

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The influence of social adversity on cardiovascular aging

Cardiovascular disease (CV) is a leading global cause of death, primarily linked to aging, but influenced by various factors like inactivity, poor diet, and limited healthcare access. Social adversities, such as social isolation and challenging childhoods, also significantly impact CV health, weakening the immune system and altering genes. Understanding how social challenges affect CV health […]

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Gestion de l’énergie thermique pour l’optimisation de la fonctionnalisation des biocapteurs plasmoniques

Ce projet porte sur la compréhension et la gestion de l’énergie thermique apportée par un laser impulsionnel (excitation très courte) pour modifier la surface d’un biocapteur. L’étudiant s’intéressera au contrôle de cette énergie (répartition et durée) pour enlever les molécules d’une surface et optimiser ensuite leur position pour le développement d’un capteur plus sensible. Des […]

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Climate change impact on groundwater quality in Southern Alberta

Access to clean and safe water resources is crucial for the progress and economic development of Alberta, Canada. Ensuring sustainable groundwater use can be a viable solution to address the regional scarcity of sufficient amounts of high-quality freshwater, particularly in certain areas of Southern Alberta where there is a moratorium on new surface water licenses. […]

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A generalizable bilevel reinforcement learning model to solve large-scale unrelated parallel machine scheduling problem with sequence-dependent setups in real-time

Our research addresses the challenges in solving large-scale parallel machine scheduling, an important combinatorial optimization problem in computer science and operations research. With applications ranging from manufacturing to healthcare and supercomputing, our goal is to provide a real-time solution for instances exceeding 1,000 jobs. In this research, we explore the application of parallel machine scheduling […]

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Synthesis of Cell-Permeable Copper Chelators for Detecting, Sensing, and Therapy

For this new international collaboration we plan to develop cell-permeable metal binding agents as therapeutics to treat Wilson’s disease. Wilson’s disease is a genetic disorder that results in the build-up of excess copper in the liver, leading to significant toxicity. By drawing on the expertise of the research teams in Canada and Brazil we plan […]

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Vers une théorisation de la coopération comme fondement des stratégies de prévention en santé au travail. Discussion des résultats dans le cadre de la clinique du travail

Ce stage s’inscrit dans le cadre d’un projet de thèse doctorale visant à théoriser la coopération au travail en analysant les processus organisationnels favorisant le développement du pouvoir d’agir collectif des enseignants et enseignantes, en encourageant leur participation active à l’amélioration de l’organisation du travail. Son objectif est également de consolider la pertinence de cette […]

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Production de matériaux biosourcés à base de tanin

L’objectif de ce projet est de développer les matériaux biosourcés en collaboration avec les membres chercheurs au Canada, en France et au Brésil. Ce volet sera divisé en trois sessions mais la stagiaire Mme Khouloud Swalmi participera à la session sur la production de matériaux biosourcés, spécifiquement de gels à base de tanins commerciaux venant […]

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Preparing bio-plastic form lignin and chitosan extracted from renewable resources

Plastics play a vital role in our daily lives, touching various sectors such as construction, healthcare, automotive, agriculture, and packaging. Packaging films, in particular, serve diverse purposes for both food and non-food items. However, the widespread use of disposable plastics leads to a significant waste issue. To address this, there’s a growing push to replace […]

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Study of extracellular vesicles in cardiometabolic disease

This project will focus on transforming scientific research excellence into improved healthspan via the development of improved diagnostics to allow personalized therapeutic strategies, with novel treatment and rejuvenation approaches targeting cardiometabolic disease. Exciting preliminary data has been generated by the York University research team. The Konkuk University research team have the established expertise to capitalize […]

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