Complexe de cuivre pour le couplage Chem-Evans-Lam

L’objectif de ce stage serait de coordonner des ligands multidentates bis(NHC) bis(ylides) à des métaux légers de première rangée pour des applications en catalyse. Idéalement, puisque le cuivre, le cobalt, le fer et le nickel sont tous stables à un état d’oxydation de 2, le même ligand pourrait être utilisé pour chacun d’eux. Ces catalyseurs […]

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Functional long non-coding RNAs in the 3D structure of the genome

Previous research has shown that most of the mammalian genome is transcribed, while most mammalian transcripts do not code for proteins and may instead be functional themselves. Non-coding RNAs play critical roles in some of the most fundamental processes in molecular biology. The vast majority of mammalian non-coding transcripts are constituted by long non-coding RNAs […]

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Hyphenated and Whole: Forms, Aesthetics, and Sociology in Korean-Canadian and Global Korean Literatures

My doctoral project aims to fill a common and critical gap between Asian-Canadian literature and global Korean-diaspora studies by undertaking the necessary examination, translation, and preservation of Korean-Canadian literature. As part of this larger project, I propose to develop my understanding of modern Korean literature, including its development, forms, and socio-cultural politics, to shape a […]

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Design and Exploration of a General Purpose Stochastic Computing Processor

The rise of Internet of Things (IoT) with millions of edge devices created per year drives the need for computing platforms that have lower power, better fault tolerance and greater computing flexibility. With more and more novel applications and algorithms being rapidly deployed, the traditional approach of using custom hardware to achieve a low power […]

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Probabilistic Image Generation from Layout

Despite significant recent progress on generative models, controlled generation of images depicting multiple and complex object layouts is still a difficult problem. Among the core challenges are the diversity of appearance a given object may possess and, as a result, exponential set of images consistent with a specified layout. In this project, we propose to […]

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An examination of post-compulsory education for migrant children in urban China

Migrant workers are an important source of labor, becoming the engine of rapid development in urban areas in China. Despite the fact they have made a significant contribution to China’s economic prosperity, they and their children have limited access to social welfares in the host cities due to their lack of local urban hukou (household […]

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Selection and Characterization of DNA aptamers for macrolide ring closure reactions

A class of compounds the work will be done are tetrahydrofuran-incorporating polyketide macrolides. This class of compounds are natural products found in diverse marine and terrestrial environments, and it has been found to show potentially useful activity in a variety of biological assays. In order to explore and expand this family of macrolides, it is […]

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Downstream purification of RNA therapeutics

Gene therapy is an expanding field that shows promise in the long term treatment of many genetic disorders. CRISPR-Cas9 technology is one way of editing the existing genome when trying to treat genetic disorder, or engineering genetic therapeutics. One area of interest is RNA therapeutics based on this technology. The Zydney and Salis lab groups […]

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Properties and behaviours of Mesenchymal Stem Cells in response to lung microenvironment in human Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening condition with a high mortality. Currently, there are no proven pharmacological therapies available for the management of ARDS patients. Mesenchymal Stem Cells (MSCs) have been shown to be interesting candidates for treating ARDS. But their therapeutic effects as demonstrated in animal models and clinical trials have been […]

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War remote from physical contact: the ideology, form and strategy in Chinese and Japanese visual propaganda during WWII

During WWII, unlike radio programming, electronic visual media were not widely popular in Chinese and Japanese citizens’ personal lives. However, visual print media provided sources from which both government and civilian organizations could develop effective platforms for publicity and propaganda. In this project, I would visit Japan and China to retrieve war period visual media […]

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The Feminist Buddha: Revisiting the Role of Gender within Buddhist Communities in Sichuan Province, China

This project will be researching gender inequality in Buddhist communities within Sichuan province, China. I will be conducting interviews with both monastic and lay practitioners to get firsthand accounts of the role of gender in Buddhist institutions. Previous scholarly work concludes there is significant gender inequality within Buddhist institutions. This project will revisit the issue […]

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