Non-Viral delivery of insulin and IL-10 to the intestine for immunotherapy for type 1 diabetes Year Two

There is increasing evidence suggesting a link exists between the gut immune system and several autoimmune diseases, including diabetes. The industrial partner of this project, enGene, has developed an effective non-viral based technology for the delivery of genes to the intestine. enGene has demonstrated the feasibility of delivering IL-10, which is an anti-inflammatory cytokine, to […]

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Dynamical decoupling for engineered dissipative process

Engineered dissipation is an important technique to prepare quantum resources, such as spin-squeezed states, for quantum sensing and computing. Compared with traditional coherent approach, engineered dissipation is generally less demanding in control precision and more robust against noise. However, the efficiency dissipative spin squeezing can be affected by unwanted interaction. It would be highly desirable […]

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Quantum error correction compiler for novel quantum computing platform

Realistic quantum computers unavoidably suffer from physical imperfections, such as environmental influence and imprecise control. An imperfect quantum computer will introduce computational error, so quantum error correction (QEC) is necessary to improve information accuracy. Standard QEC assumes an implementing circuit that involves a typical set of logic gates. However, not all the standard gates can […]

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Investigating the biophysics and structural basis for state dependent drug blockade of persistent/late sodium current (INa(P)) in the heart using photoactivatable crosslinking unnatural amino acidsYR2

Electrical activity in the heart is controlled by the concerted activity of many proteins called ion-channels that regulate the transfer of different ions across cell membranes. Recently, researchers in biomedical science have identified that a particular component of sodium carrying ion-channel activity (called the persistent or late sodium current also known as INa(P)) played a […]

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In vitro tissue culture methods for ornamental propagation and new varietal development

The innovation of plant cell and tissue culture (TC) techniques has supported plant propagation programs and allowed for the development of new ornamental varieties. Van Belle Nursery is interested in adapting TC as a method of cultivation but lack the technical expertise and understanding of infrastructure requirements to establish an on-site TC program. Specifically, they […]

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Isolation, characterization and culture maintenance of stem cells from human hair follicle mesenchyme Year Two

Stem cells and other pluripotent cells are under active investigation for the development of new therapeutic treatments to regenerate and repair diseased and damaged tissues. Published studies indicate that some mesenchymal cells derived from adult human hair follicles exhibit stem cell properties and can form different cells types if they are given specific biological signals […]

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3D printing of thixotropic hybrid siloxanes for transparent applications

Hard and transparent 3D printing materials are in demand in applications such as durable device passivation and transparent architectures. To replace 3d printable glass or ceramic, which has the disadvantage of undergoing high-temperature post-treatment after printing, the study of hard, transparent, and thermally resistant 3D printing materials will be conducted in this project. To achieve […]

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30-year Retrospective Taphonomic Study on Aquatic Body Decomposition (1990 – 2019)

The study of human body decomposition serves an important role in helping death investigators estimate the time since death, the context of the death, and postmortem movement of deceased individuals. Experimental submergence studies have helped distinguish decomposition effects of marine, freshwater, and laboratory-induced taphonomy from terrestrial contexts, but few actual cases of recovered human remains […]

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Leveraging the Canadian Longitudinal Study on Aging to Support Healthy Aging Programming in the Community-Based Seniors’ Services Sector

Transportation problems are one of the most common barriers, after health problems, that prevent older Canadians from participating in more social, recreational, or group activities. United Way Healthy Aging is working closely with the community-based seniors’ services sector to bring solutions to seniors’ transportation. Through the Better at Home program, United Way Healthy Aging supports […]

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Bomford Studios Digester

In order to address the growing need for urban composting of organic matter, Bomford Studios has successfully created a working prototype putrescent organics processing unit (the Loki Digester), which breaks down organic matter into fertilizer suitable for both gardens and large-scale farms. Working with Camosun Innovates, Bomford intends to create a more robust, user-friendly, and […]

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Development of a bio-based non-isocyanate polyutherane

This project aims to innovate a Made-in-Canada methodology for producing non-isocyanate polyurethane (NIPU) to replace traditional polyurethane (PU) rigid foam which is produced through a hazardous process from toxic materials such as isocyanates and phosgene.1 We aim to partner with Polychem Consulting Solutions Ltd, a privately held Canadian company based in Vancouver, BC and a […]

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