Distributed Extremum Seeking Control Using Observer-based Methods

In this project, we propose a new technique for controlling the formation of high-altitude balloons. Instead of using traditional high-pass filters, we suggest using high-gain observers to improve the accuracy and effectiveness of extremum-seeking control. Our research on this multi-agent approach aligns with the main objectives of Stratotegic Inc, which focus on the research and […]

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An integrated and adaptive study examining central and peripheral mechanisms of chronic pain in knee osteoarthritis patients

It has been estimated that 300 million people worldwide have osteoarthritis (OA) and this has increased by 97% over the past 25 years. The pain and loss of mobility experienced by people with knee OA can seriously reduce quality of life, while pain management causes significant healthcare spending. Unfortunately, the pain associated with OA is […]

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Development of novel chemical probes and SARS-CoV-2 antiviral therapeutics through engineered HAI-2 protein inhibitors of TMPRSS proteases

Respiratory viruses exploit the biological activity of human proteins present at the surface of airway cells to allow viruses to penetrate that physical barrier and subsequently replicate in infected cells. It has been established that a family of human proteins, the type 2 transmembrane serine proteases, are directly responsible for this viral entry, but they […]

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Embedding Social and Health Equity into Greenspace Programs and Policies

Experiencing and accessing nature has been shown to promote individual and communal physical and mental well-being. However, these benefits are not universally enjoyed due to social inequities. There are limited tools and strategies to ensure that greenspace programs and policies have positive social and health equity impacts. During the COVID-19 pandemic, we saw the confluence […]

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Characterization of PATL2’s role in Human Fertility for the Development of Non-hormonal Contraceptives

Norethindrone, the first oral contraceptive, is noted as one of the most pivotal molecules to be introduced into society. When introduced in 1960, norethindrone caused a societal paradigm shift by allowing for family planning and providing women with more agency over their reproductive system. Unsurprisingly, the women’s liberation movement, rise of feminism, and the increased […]

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Developing an integrated hydrogen bio-methanation process to enhance and upgrade biogas production in an anaerobic digestion process

The increased energy prices and effects of climate change are severely impacting the day-to-day lives of Canadians. Moreover, essential sectors such as agriculture release substantial amounts of greenhouse gases, adding to climate change challenges. Hence, investing in local and sustainable energy sources is more critical now than ever to reduce these burdens. Therefore, biogas generation […]

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Photonic integrated circuits for AR display light engines

Augmented reality (AR) is poised to transform human interactions. This project aims to explore the use of photonic integrated circuits (PICs) for the development of compact and high-performance image projectors, also called “light engines”, for AR glasses. PICs are a type of integrated circuit that uses light instead of electricity to perform various functions, such […]

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Development of low-cost and lithium-metal stable halide solid electrolytes for high-performance all-solid-state batteries

Conventional Li-ion batteries using liquid electrolytes (LEs) are suffering from insufficient energy density and safety issues when used for the flourishing market of electric vehicles (EVs). Replacing LEs with solid-state electrolytes (SSEs) to fabricate all-solid-state lithium batteries (ASSLBs) has been regarded as an essential route to improve energy density and safety. Basically, a qualified SSE […]

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Cortical changes measured with TMS and MEG following 3-weeks of hand movement training using a novel passive device

Stroke is the leading cause of adult disability, with long-term hand function impairments being the most common symptom among stroke survivors. As hand function plays a vital role in performing everyday activities, individuals with stroke face a significant impact in their quality of life including their ability to maintain independence, employment, and socially connectedness. To […]

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Assessing scientific rigour and 3Rs implementation in Canadian research: Investigating animal use protocols and stakeholder perspectives

Millions of animals are used in research each year. This practice is justified by the expectation that the benefits of such research will be significant, outweighing the harms imposed on animals during experiments. Indeed, animal research has led to countless improvements in human health and quality of life. However, there is growing concern that current […]

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