Parkinson’s disease (PD) is the 2nd most common neurodegenerative disorder, affecting greater than 1% of people over 60. As occurrences are predicted to double in the next 20 years, there is a critical need for the development of prophylactic and/or therapeutic interventions. We have recently identified two enzymes, USP8 and AMPK, that interact and may […]

In recent years, research in computer algebra has expanded beyond its traditional territories, such as exact linear algebra and formal solutions of partial differential equations, to enter new arenas, such as symbolic analysis and polyhedral geometry. The proposed research projects will expand the scope of computer algebra systems (CAS) into these two new areas. They […]

Periprosthetic Joint Infections (PJIs) are infections involving an implanted joint prosthesis and surrounding tissue that occur following joint arthroplasties. Management of these infections is challenging and often surgical due to the antibiotic-resistant nature of the biofilm produced by infecting organisms. In 2019-2020, more than 63,000 Total Hip Arthroplasties (THAs) and 75,000 Total Knee Arthroplasties (TKAs) […]

Solid-state nanopores—tiny holes in thin glass similar in size to biomolecules like proteins or DNA—are poised to disrupt many essential growth markets, including genomics and proteomics, personalized medicine, point-ofcare diagnostics, and next-generation information storage. While holding great promise as a broadly applicable disruptive technology, solid-state nanopore sensors are individually failure-prone, requiring use of many in […]

Currently, one of the primary barriers to purchase through our website is the virtual fitting process, which requires a live virtual meeting with a stylist. Developing an artificial intelligence that would capture body measurements would allow us to streamline the fitting process for our customer, resulting in an increase in customer experience and sales. The […]

A critical part of our success in building one of the largest Brokerages in Canada has been the ability to attract and retain excellent Mortgage Agents, and assist them in their individual success. A key element of that retention and acquisition and assistance has been the power of our proprietary software systems. Our current system […]

CommNeeds is a community resource-sharing platform that enables, local businesses, startups, small home-based entrepreneurs and community members to access skills and resources available in their vicinity. CommNeeds nurture micro-economy with the exchange of services locally and also establish a mechanism to equip the future workforce with the skills and experience they need. COVID and other […]

This project will analyse Canada’s official multiculturalism policy and its impact on the National Arts Centre’s English language theatre program. The National Arts Centre Archival holdings will be utilized for research to assess the diversity of persons from ethnic minorities and Indigenous groups as actors, directors, and authors of the plays that have been performed […]

The design optimization process of photonic and optoelectronic devices can be time consuming. The modeling of these electrically-long devices is time-intensive. Accurate time-domain and frequency-domain simulation tools such as the finite difference time domain (FDTD) method and the finite element method (FEM) are usually utilized to model these devices. These methods require fine meshing to […]

Rare cannabinoids are currently gaining popularity for their potential uses in pharmaceuticals, therapeutics and cosmetics. Traditional cannabis companies are currently unable to produce these compounds and the demand is expected to increase significantly in the future. This highlights the need for new, innovative solutions to solve this problem. Using synthetic biology, the intern will develop […]

Anastomotic Leakage is a common complication that can occur shortly after surgery and lead to increased mortality rates if it is detected too late. The current method of detection relies on monitoring clinical symptoms and visual inspection of the surgical drain fluid, but this process is often delayed and reactive. NERv Technology Inc. is dedicated […]

Subtitles are typically generated postproduction and might be mis-aligned with the audio track. Alignment of subtitles to audio is a task which aims to produce accurate timings of the words within a subtitle track given a corresponding audio track. The alignment task is of significant relevance to Bell media. Semi–automated solutions exist, and they involve […]