Metabolic differences during metastasis of epithelial ovarian cancers

Epithelial ovarian cancer (EOC) is a debilitating disease that has a 5-year survival rate of only 44%, making it the fifth most lethal cancer in women. A major reason for this low survival rate is the high rate of metastasis, where cells detach from the primary tumour site on the ovary and reattach at secondary […]

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Investigating AKT1-dependent pathways to regulate cellular metabolism

The serine/threonine kinase AKT1 is a key mediator of cell growth and survival processes including glucose metabolism, apoptosis, transcription, proliferation, and migration. AKT1 is activated by phosphorylation at two key regulatory sites, Threonine308 and Serine473, that are both used as clinical diagnostic markers for cancer. AKT1 also plays an important role in glucose metabolism by […]

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Extrusion printing of hydrogels for cell therapies

Hydrogels have been widely researched as biomaterials for cell and drug delivery. Allarta has developed polymer-based capsules, based on pioneering research at McMaster University, with a range of diffusion profiles. Allarta has shown the ability of these hydrogels to support different mammalian cell types including stem cells and islets. Furthermore, such cell-containing hydrogels have been […]

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Development and evaluation of WinSport’s IPLAY program: A mixed methods examination of a physical literacy-based initiative for newcomer youths

Physical literacy (PL) programs focus on developing competence, confidence, and the knowledge to be physically active (PA) across the lifespan. Given that current rates of PA among children are continuing to decline, with only 9% of children meeting the Canadian PA guidelines, PL programs provide a unique opportunity to facilitate a lifelong interest in PA. […]

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Improving and scaling up cycling infrastructure under pandemic urbanism

In response to the present Covid-19 pandemic and the need to decarbonize the transport sector, city leaders and communities are rethinking past assumptions regarding transport planning and infrastructural development and have renewed interest in promoting cycling as a sustainable transport mode. Infrastructural interventions that improve safety and comfort and widen access to cycling are necessary […]

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Assistive Software for Coronary Artery Bypass Graft Angiography

Due to the unpredictable location of coronary artery bypass grafts (CABG), angiography for CABG patients costs catheterization labs additional time, poses an added risk to patients, and incurs extra costs, therefore using additional resources at Sunnybrook Hospital and at a national scale. The development of an assistive software product that helps cardiologists find free graft […]

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BIPOC Leadership Energies

The BIPOC Leadership Energies (BLE) project will create a strategy for generating leadership networks and career advancement pathways for emerging female-identified and/or non-binary BIPOC leaders. The framework will outline goals, structure, resources and implementation steps to build and sustain multi-year inter-organizational coaching networks for BIPOC staff. BLE is a collaboration between 5 community service agencies. […]

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Sliike Project – Mobile Apps/Website Design & Marketing Intern

Sliike Corporation is a startup B2B/B2C online marketplace and e-commerce company based in Quebec, Canada. We own a technology platform (App and website) that promote effortless transaction of beauty services, sales of beauty product and advertisement of global brands in cosmetics, fashion, lifestyle, home care and personal care. Our platform also serves as a place […]

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Thermodynamic investigation into the recovery of rare earth elements

The proposed research aims to contribute to the development of a recycling process for waste magnets. The proposed method is based on slag treatment which is a high temperature process for separation of one element from another based on their difference in oxygen affinity. For example, the affinity of neodymium for oxygen is significantly higher […]

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Design and development of machine learning and signal processing algorithms for a wearable device (Watch HOP) for critical care, surgery, and chronic disease monitoring

Diabetes is a chronic illness characterized by elevated levels of blood glucose, accompanied by disturbed metabolism of fats and proteins. In the present project, a non-invasive wrist-worn device (Watch HOP) will be designed and fabricated to obtain physiological data (digital biomarkers) from participants to enable the creation of an algorithm that will ultimately allow to […]

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Stereo (Multi-view) DepthIQ and its Application in SLAM

Our partner organization has developed a new type of camera, one where depth information is part of a single lens/sensor construction, meaning that there are no occlusions or shadows which plague stereo cameras, there is no requirement to light the scene as well time-of-flight cameras, and the expense is low compared to light-field cameras. Currently […]

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