Harnessing epigenetics to improve muscle stem cells function in degenerating myopathies

Duchenne Muscular Dystrophy (DMD) is an incurable progressive myopathy, caused by the absence of the dystrophin protein. It is characterized by permanent myofiber necrosis, leading to continuous activation of muscle stem cells (MuSCs), that eventually cannot support muscle repair leading to replacement of the muscle by fibro/fatty tissue. We have observed that epigenetic changes in […]

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Édition critique de «La Sauvagesse» d’Alain-René Lesage

Mon projet de recherche consiste à procurer une édition de la pièce La Sauvagesse, qui fait partie du recueil Le théâtre de la foire, ou l’opéra-comique revu et corrigé par M. Alain-René Le Sage (1668-1747). Bien qu’elle fasse partie d’une catégorie de théâtre plus modeste, elle donne une représentation exotique des Amériques sous l’Ancien régime. […]

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Development of Novel Cellulose Bioprinting Materials Using Thilo-ene Click Chemistry for Application in 3D Printing/Structuring

Recently, new development of 3D printing and patterning technologies offering advantages such as low cost, rapid prototyping, and high resolution have captured the attention of consumers, producers, and scientists alike. Although 3D printing and structuring methods have evolved over time, the materials used have not. Cellulose is a natural material that exists all around us […]

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KINARM Standard Tests’ Task Scores: towards a validated and effective tool for communicating to clinical communities KINARM measures of brain function

KINARM Labs™ provide robust and objective measures of brain function and dysfunction by the precise measurement of human behavior with robotics. Created by neuroscientists, KINARM Labs allow clinician-scientists to detect and quantify the sensory, motor and cognitive impact of a diverse range neurological impairments caused by stroke, cardiac arrest, TIA, mTBI, concussion, MS or Parkinson’s […]

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Expert Gestures for Multi-touch Interaction

Modern smartphones and tablets, and many notebook computers rely on multitouch interaction to augment keyboard and mouse input. Multi-touch gestures typically consists of taps and swipes – simple gestures that don’t exploit the full range of technical and human capabilities. In earlier work, we determined that users are willing to learn expert-level gestures, but often […]

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Measurement Verification And Modelling of W-Band Imager and Harvester

Beyond the spectrum of visible light lies a window of frequencies called the W-Band which illuminates a world normally unseen to the naked eye and can be the vessel for energy without wires. In order to see this world normally unseen, we have developed a unique circuit topology which has shown signs of truly state-of-the-art […]

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UV-CHLORINE ADVANCED OXIDATION FOR WATER TREATMENT

The student will work in a drinking water engineering research laboratory at the University of Toronto to explore an aspect related to the novel use of ultraviolet light and chlorine to destroy hard-to-treat contaminants in drinking water. Previous work by this lab has shown that this form of treatment can be effective, but it is […]

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High energy density lithium ion cells/batteries with excellent electrochemical performance and safety

Li-ion batteries (LIBs) are currently the most important power source for a wide variety of applications such as cell phones, laptops, computers and other portable electronics. They are also considered as very promising storage/power systems for future electric/hybrid-electric powered transportation. Although clever cell design and improvements in cell subcomponents can bear potential for volume and […]

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High energy density lithium ion cells/batteries with excellent electrochemical performance and safety – Year two

Li-ion batteries (LIBs) are currently the most important power source for a wide variety of applications such as cell phones, laptops, computers and other portable electronics. They are also considered as very promising storage/power systems for future electric/hybrid-electric powered transportation. Although clever cell design and improvements in cell subcomponents can bear potential for volume and […]

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