Positive pombe: engineering anti-depressant molecules in fission yeast

The COVID-19 pandemic has increased depression and anxiety in Canada, adding to the current opioid drug dependency crisis. Mental health supports can be used with drug options to relieve symptoms and promote better health. Some cases of depression are resistant to treatment, and alternatives are needed that bring patients relief. Psilocybin is a compound found […]

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Reliability Analysis of Gallium Nitride (GaN) Devices Using Data Analysis Methods

Gallium nitride (GaN) high-electron-mobility transistors (HEMTs) are good candidates to replace the traditional silicon-based transistors. Although these devices show superior performances compared to Si and SiC-based devices, they suffer from some reliability issues. The aim of this research project is to improve the performance of the GaN HEMTs and enhance their reliability by performing a […]

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Nonlinear Section Model Tests in the Wind Tunnel for Cable-Supported Bridges

Due to the length and intrinsic flexibility of cable-supported bridges, wind causes serious challenges to designers of such structures. To ensure the safety of these bridges, it is common practice to test scale models of bridges in the wind tunnel. As bridges are getting longer, simplifications used for typical wind tunnel test become questionable. Therefore, […]

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Novel Adhesive For Use In Sternal Fixation and Application

Median sternotomy is the standard approach in heart surgery. Over 1.5M operations are performed worldwide annually; 45K in Canada. Wires are used post-operatively to close the sterna, leading to instability, micro-motion and pain. Alternative techniques lack effectiveness or are cost prohibitive. Glass polyalkenoate cements (GPCs) are used in restorative dentistry, orthodontics and ear, nose and […]

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Accelerated Maturation of Rye Spirits

Whisky is made by a process of fermentation, distillation, and maturation. The last step is by far the most time-consuming part of this process. In order for maturation to occur, the distilled spirit must sit in a wooden barrel for years, during which the spirit takes on the familiar colour and taste of whisky. This […]

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Intraocular Pressure Monitoring Microfluidic Contact Lens

The proposed research project is to design a microfluidic contact lens that will be used to track the fluctuations in intraocular pressure. Intraocular pressure is the primary factor to monitor the progression of glaucoma, which is a chronic disease that leads to permanent vision loss and currently has no cure, making early and frequent testing […]

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Prevalence of moderate-to-severe Osteoarthritis pain of the hip and knee by Index Joints in Canadian Primary Care: A proof of concept study from the Canadian Primary Care Sentinel Surveillance Network

Osteoarthritis (OA) is a common disease in middle-aged and older Canadians attending primary care practitioners. As the Canadian population ages and with increasing obesity, OA will become an increasing burden for individuals and the health care system. Given the potential of Electronic Medical Record (EMR) data for surveillance of the population that is at high […]

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Assessing forest harvesting impacts on furbearer habitat at the scale of Indigenous traplines – A case study in Indigenous consultation

The “Assessing forest harvesting impacts on furbearer habitat at the scale of Indigenous traplines – A case study in Indigenous consultation and forest conservation” project is planned to enhance the understanding of Indigenous rights holders concerning forest management activities that impact the distribution of forest types and ages upon which the forest dwelling wildlife that […]

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Modélisation du contrôle du mouvement des membres supérieurs à l’aide de réseaux de neurones et modèles biomécaniques précis

Le but de ce projet est de développer des modèles précis du mouvement des membres supérieurs en utilisant des modèles précis de la biomécanique des membres supérieurs et des algorithmes de machine learning. Ces modèles seront utilisés afin de mettre en place des protocoles expérimentaux permettant de mieux comprendre la manière avec laquelle le système […]

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