Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer – Year two

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

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Redefining Recreational River Waves

Wave surfing was traditionally restricted to oceans. Nowadays it is becoming more and more popular in rivers. Although there are some natural surfable waves in rivers, human constructions can provide waves even where they do not naturally exist. However, there is not enough academic support for design and construction of these waves. In this project, […]

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Promoting economic development and vitality of rural communities in Ontario

Many rural regions do not have a sufficient labour force providing the skills that rural businesses need. Many job vacancies go unfilled or are filled by less than ideal candidates. This research looks at strategies to attract and retain the workers that Ontario rural communities need to generate economic development and vitality. By engaging local […]

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Root associated microbiome of trees growing in a fractured bedrock toluene phytoremediation site

Phytoremediation (plant-based environmental cleanup) is a green, cost-effective alternative to conventional methods for contaminated site cleanup, which often involve extensive, community-disruptive, industrial efforts. Deep-rooted trees, such as hybrid Canadian poplars, can effectively be used to contain and clean up petroleum-derived contaminants in soil and groundwater resources. The proposed research project is aimed at verifying the […]

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Improving cancer care operations

This project is composed of three sub-projects, all sharing the goal of improving cancer care operations. The first project aims to improve the scheduling of ambulatory clinics at Princess Margaret Hospital and Women’s College Hospital. Better scheduling will result in less overtime, improved utilization of shared resources, and increased patient satisfaction. The second project is […]

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Targeting platelet-neutrophil axis: a novel therapeutic approach for Scleroderma

Scleroderma or Systemic Sclerosis (SSc) is an autoimmune disease characterized by progressive fibrosis of skin and multiple internal organs and prominent and often severe alterations in the microvasculature. Although SSc is the third most common systemic inflammatory autoimmune disease, there is currently no effective disease-modifying therapy for SSc. The overall objective of this project is […]

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Harnessing digital tools for Cultural Heritage Promotion and Conservation

Cultural Heritage is the legacy of the past that needs to be protected and tarnsmitetd to future generation, its conservation makes part of the sustainable development goals of the United Nations Conservation. This proposal is focused on the development of a digital information platform for conveying the importance of conservation and protection of cultural heritage […]

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NMR Chemical Shift Prediction for Diamagnetic Li-Ion Solid-State Electrolytes

This research is focused on understanding the microscopic mechanisms of lithium ion dynamics in novel solid-state electrolyte materials, which have a wide array of potential applications ranging from electric vehicle batteries to grid storage of renewable energy. A major gap in the development of all-solid-state batteries, which will be safer and more energy-dense than state-of-the-art […]

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Beta testing an electronic detector for liquid chromatography and developing an electronic detector for gel electrophoresis in partnership withend users

In this internship, UNS-Tech will partner with Profs. Cynthia Goh and David McMillen to use UNS-Tech’s electronic detection technology to detect molecules, including proteins, polymer nanoparticles and DNA, that are of interest in their research. UNS-Tech’s state-of-the-art electronics-based detectors for HPLC and gel electrophoresis will be employed in Prof. Goh’s and Prof. McMillen’s labs, respectively. […]

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